Protein Alignment veil and Nt5e

DIOPT Version :9

• Sequence 1: NP_001286533.1
• Gene: veil / 36968
• FlyBaseID: FBgn0034225
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_035981.1
• Gene: Nt5e / 23959
• MGIID: 99782
• Length: 576
• Species: Mus musculus
• Alignment Length: 608
• Identity: 240/608 - (39%)
• Similarity: 337/608 - (55%)
• Gaps: 58/608 - (9%)

  Fly     1 MLPA-----RGLLIGSCCLLALLIHPVQPNPIAPRAEVAAEFIILHNNDMHARFEQTSVTSGTCS 60
            |.||     :.||:....||     |..|      |..|.|..|||.||:|:|.||||..|..|
Mouse     1 MRPAAAKVPKWLLLALSALL-----PQWP------AASAWELTILHTNDVHSRLEQTSDDSTKC- 53

  Fly    61 KEEANTDQCYGGFARVAYEVRKYRKEAEEGGTPVFYLNAGDTYTGTAWFTVYKDKIASAFLNKLS 125
               .|...|.||.||:..:|::.|||...    |.:|:|||.|.||.||||||....:.|:|.|.
Mouse    54 ---LNASLCVGGVARLFTKVQQIRKEEPN----VLFLDAGDQYQGTIWFTVYKGLEVAHFMNILG 111

  Fly   126 PDAISLGNHEFDQNVEGLV-PFLNAVEFPVLACNLNLTDVPEMAAAKQLAN----STILERNGVK 185
            .||::|||||||..||||: |.|..|:||:|:.|:....    ..|.|::.    |.:|...|..
Mouse   112 YDAMALGNHEFDNGVEGLIDPLLRNVKFPILSANIKARG----PLAHQISGLFLPSKVLSVGGEV 172

  Fly   186 VGVIGYLTPDTKVLAF-RNKVEYEEEIVSINAEAAKLKAQGINIIIALGHSGYQKDQEIAMNCPE 249
            ||::||.:.:|..|:. ...:.:|:||.::..|..|||...:|.||||||||::.|:.||.....
Mouse   173 VGIVGYTSKETPFLSNPGTNLVFEDEISALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRG 237

  Fly   250 VDIVIGGHSHTFLDANQPVADPTDSDPEAVRGPYPTTVVQASGKKVPVVQAYAYTKYLGKIHVQF 314
            ||||:||||:|||....|   |:...|   .|.||..|....|::||||||||:.||||.:.|:|
Mouse   238 VDIVVGGHSNTFLYTGNP---PSKEVP---AGKYPFIVTADDGRQVPVVQAYAFGKYLGYLKVEF 296

  Fly   315 DAEGNLIEFDGAPILLNASVAQEQDLLDLLDEYRPKLDELENTVLGYTKVFLEGG-NICRMRECN 378
            |.:||:|...|.|||||:|:.::..:...::::|.|||......||.|.|:|:|. ..||.||||
Mouse   297 DDKGNVITSYGNPILLNSSIPEDATIKADINQWRIKLDNYSTQELGRTIVYLDGSTQTCRFRECN 361

  Fly   379 LGNLVTDAMIYSRVLENKGGEFWTDTAIAFMQGGGIRGSVDKKDDGVINGATLLAVLPFENNLYV 443
            :|||:.||||.:. |.:....||...::..:.|||||..:|:|::|.|....|.|||||.....:
Mouse   362 MGNLICDAMINNN-LRHPDEMFWNHVSMCIVNGGGIRSPIDEKNNGTITWENLAAVLPFGGTFDL 425

  Fly   444 TRILGSTLLAALEHSASVRLQDSNGGFLQMSGLRVVYNYNNEQGKRVVSAQALCASCAVPTYKSI 508
            .::.||||..|.|||.. |...|.|.|||:.|:.|||:.|.:...|||..:.||..|.||.|:.:
Mouse   426 VQLKGSTLKKAFEHSVH-RYGQSTGEFLQVGGIHVVYDINRKPWNRVVQLEVLCTKCRVPIYEPL 489

  Fly   509 NETALYQVIVPQFLLEGGDGYTLIEESDPFTESMQRN----DLNATMEYLKQRHFVYPEIEERIV 569
            ....:|:|.:|.:|..||||:.:|::     |.::.:    |::...||:.:...|||.:|.||.
Mouse   490 EMDKVYKVTLPSYLANGGDGFQMIKD-----ELLKHDSGDQDISVVSEYISKMKVVYPAVEGRIK 549

  Fly   570 IHEKADTGSASGIVASISLLLLS 592
            .      .:||....|..|::||
Mouse   550 F------SAASHYQGSFPLVILS 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
veil	NP_001286533.1	UshA	14..556	CDD:223808	223/552 (40%)
		MPP_CD73_N	37..330	CDD:277354	130/298 (44%)
		5_nucleotid_C	358..528	CDD:280945	71/170 (42%)
Nt5e	NP_035981.1	UshA	21..534	CDD:223808	220/543 (41%)
		MPP_CD73_N	31..312	CDD:277354	130/298 (44%)
		5_nucleotid_C	354..509	CDD:280945	65/156 (42%)
		Substrate binding. /evidence=ECO:0000250	502..508		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849153
Domainoid	1	1.000	168	1.000	Domainoid score	I3812
eggNOG	1	0.900	-	-		E1_COG0737
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1895
Inparanoid	1	1.050	404	1.000	Inparanoid score	I1890
Isobase	1	0.950	-	0	Normalized mean entropy	S6498
OMA	1	1.010	-	-		QHG52881
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001036
OrthoInspector	1	1.000	-	-		otm42593
orthoMCL	1	0.900	-	-		OOG6_101038
Panther	1	1.100	-	-	O	PTHR11575
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5252
SonicParanoid	1	1.000	-	-		X1114
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740