DRSC/TRiP Functional Genomics Resources

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Protein Alignment qkr54B and QKI

DIOPT Version :9

Sequence 1:NP_001261050.1 Gene:qkr54B / 36966 FlyBaseID:FBgn0022987 Length:617 Species:Drosophila melanogaster
Sequence 2:NP_006766.1 Gene:QKI / 9444 HGNCID:21100 Length:341 Species:Homo sapiens


Alignment Length:348 Identity:90/348 - (25%)
Similarity:153/348 - (43%) Gaps:83/348 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 GNVQINEKAN---EYIRDCMAERNRMDRK------FPIAEKLLEGEIEKVQTTGRIPSREQKYAD 112
            |.::..||..   :|:...|.::..|...      |...|:||:.||.:|        |:..|.|
Human     3 GEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRV--------RKDMYND 59

  Fly   113 IYR--------EKP------LRISQRVLVPIREHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVL 163
            ...        |.|      :::.:::.||::|:|.|||||::|||:|.:.::|:.||.||:.|.
Human    60 TLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVR 124

  Fly   164 GRNSMRDRVKEEELRSSKDPKYAHLNSDLHVEISTIAPPAEAYARIAYAMAELRKYLIP--DSND 226
            |:.||||:.|||:.|..  |.:.|||.||||.|:.......|..::..|:.|::|.|:|  :..|
Human   125 GKGSMRDKKKEEQNRGK--PNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGED 187

  Fly   227 IIRQEQLRELMDSTSLNDNDNAKS---GYKKTSHMQGGNNVLGGGSINPIGGVKNTPHHSYRSSQ 288
            .:::.||.||........:.|.||   .:...:..|....::.|.:  |:     .|..:.|:..
Human   188 SLKKMQLMELAILNGTYRDANIKSPALAFSLAATAQAAPRIITGPA--PV-----LPPAALRTPT 245

  Fly   289 PSSFSKNVLAPKQKVMSILEKARTAM---------DETYGRGYDDGLGYDPHQSYDSYSYGTHGH 344
            |:.         ..:|.::.:.:||:         ......|.:.||.|.|::    |.|..   
Human   246 PAG---------PTIMPLIRQIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYE----YPYTL--- 294

  Fly   345 GPHGP----------PANILGGV 357
               .|          |:.:||.|
Human   295 ---APATSILEYPIEPSGVLGAV 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
qkr54BNP_001261050.1 Qua1 68..117 CDD:292891 13/62 (21%)
SF1_like-KH 122..237 CDD:239088 47/116 (41%)
QKINP_006766.1 STAR_dimer 10..66 CDD:406848 14/63 (22%)
Qua1 domain, involved in homodimerization. /evidence=ECO:0000250|UniProtKB:Q17339 11..82 15/78 (19%)
KH-I_Hqk 81..183 CDD:411893 43/103 (42%)
Qua2 domain, involved in RNA binding. /evidence=ECO:0000269|PubMed:23630077 182..213 8/30 (27%)
PHA03247 <211..314 CDD:223021 21/128 (16%)
SH3-binding 276..279 0/2 (0%)
Quaking_NLS 312..341 CDD:406855 2/3 (67%)
Nuclear localization signal. /evidence=ECO:0000250 324..330
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165155037
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5176
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.740

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