DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qkr54B and khdrbs2

DIOPT Version :9

Sequence 1:	NP_001261050.1	Gene:	qkr54B / 36966	FlyBaseID:	FBgn0022987	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_001072215.1	Gene:	khdrbs2 / 779662	XenbaseID:	XB-GENE-490722	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	362	Identity:	136/362 - (37%)
Similarity:	194/362 - (53%)	Gaps:	61/362 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EYIRDCMAERNRMDRKFPIAEKLLEGEIEKVQ-TTGRIPSREQKYADIYREKPLRISQRVLVPIR 130
            :|:.:.|||::.:|..|..|.:||:.||.|.| :.|.....|:||.||...|.:::|:|||:|::
Frog     5 KYLPELMAEKDSLDPSFVHAMRLLDEEIVKFQDSEGNKEDGEKKYLDIISNKNIKLSERVLIPVK 69

  Fly   131 EHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVLGRNSMRDRVKEEELRSSKDPKYAHLNSDLHVE 195
            ::||||||||||||:||||:||||||..||::||:.||||::||||||.|.:.|:|||:.:|||.
Frog    70 QYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKIKEEELRKSDEAKHAHLSDELHVL 134

  Fly   196 ISTIAPPAEAYARIAYAMAELRKYLIPDSNDIIRQEQLRELMDSTSLNDNDNAKSGYKKTSHMQG 260
            :...|||.|||:|:::|:.|::|:|:||.||.|||||||||   :.||.:|:::.|  |.:..:|
Frog   135 LEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLREL---SYLNGSDDSERG--KGTRGRG 194

  Fly   261 -------GNNVLGGGSINPI---GGVKNTPHHSYRSSQPSSFSKNVLAPKQKVMSILEKARTAMD 315
                   ..|  .||.|:|.   .|...|..........|:.::.:..|:.|........|....
Frog   195 IRVPSTPSRN--RGGVISPAFPGRGASATRGAPITRGTISTVARGIPTPRAKAAPTTPGYRLPPP 257

  Fly   316 ---ETY-GRGYDDGLGYD-PHQSYDSY------------SYGTHGHGPHGPPANILGGVGGISGG 363
               ||| ..|||||.|.| ..||||.|            .|..:.||.:....|
Frog   258 LTIETYDDYGYDDGFGEDYDEQSYDIYENNYNSQTQSVSEYYDYEHGTNEESYN----------- 311

  Fly   364 GGRGGHYESSDYEPDY----------GRREYYQHSPG 390
                 |||..::....          .|..|.:|..|
Frog   312 -----HYEQEEWSKSRSTLKAPLQRPARAGYREHPYG 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qkr54B	NP_001261050.1	Qua1	68..117	CDD:292891	19/49 (39%)
qkr54B	NP_001261050.1	SF1_like-KH	122..237	CDD:239088	72/114 (63%)
khdrbs2	NP_001072215.1	Qua1	5..57	CDD:374463	19/51 (37%)
		SF1_like-KH	61..180	CDD:239088	74/121 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..224		13/49 (27%)
		Sam68-YY	263..317	CDD:374636	20/69 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..345		4/23 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	88	1.000	Domainoid score	I7806
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3883
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9347
Panther	1	1.100	-	-	LDO	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.070