DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qkr54B and khdrbs2

DIOPT Version :9

Sequence 1:	NP_001261050.1	Gene:	qkr54B / 36966	FlyBaseID:	FBgn0022987	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_001070758.1	Gene:	khdrbs2 / 768147	ZFINID:	ZDB-GENE-061013-497	Length:	346	Species:	Danio rerio

Alignment Length:	319	Identity:	131/319 - (41%)
Similarity:	188/319 - (58%)	Gaps:	55/319 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 NEYIRDCMAERNRMDRKFPIAEKLLEGEIEK-----VQTTGRIPSREQKYADIYREKPLRISQRV 125
            ::|:.:.:||:..:|..|..|.:||..||||     ::..|.:    :||.||...|.:::|:||
Zfish     4 DKYLPELVAEKESLDASFVHAMRLLAEEIEKFEGDELRKDGEV----KKYLDIISNKNIKLSERV 64

  Fly   126 LVPIREHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVLGRNSMRDRVKEEELRSSKDPKYAHLNS 190
            |:|::::||||||||||||:|||::||||||..||::||:.||||:.||||||.|.:.|||||::
Zfish    65 LIPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSN 129

  Fly   191 DLHVEISTIAPPAEAYARIAYAMAELRKYLIPDSNDIIRQEQLRELMDSTSLNDNDNAKSG---- 251
            ||||.|...|||.|||:|:::|:.|::|:|:||.||.|||||||||   :.||.:|:...|
Zfish   130 DLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLREL---SYLNGSDDPSRGRSAR 191

  Fly   252 -----YKKTSHMQGGNNVL-----GGGSINPIGGVKNTPHHSYRSSQPSSFSKNVLAPKQKVMSI 306
                 ...|:..:|..:..     |.|:..|.|.|      |.|:|.|:. ::.|.||:.:..:.
Zfish   192 GRGLRLTSTASPRGRGSAAPPAPPGRGAAAPRGTV------SSRTSVPTP-ARGVSAPRTRGTAG 249

  Fly   307 LEKART----AMDETY-GRGYDDGLGYD---PHQSYDSY------------SYGTHGHG 345
            ....|.    |..:|| ..||||  |||   ..|||:||            .|..:|||
Zfish   250 TPGYRAPSLQATHKTYEDYGYDD--GYDGEYDDQSYESYDDNYSNQSKSVSEYYEYGHG 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qkr54B	NP_001261050.1	Qua1	68..117	CDD:292891	17/53 (32%)
qkr54B	NP_001261050.1	SF1_like-KH	122..237	CDD:239088	74/114 (65%)
khdrbs2	NP_001070758.1	Qua1	6..57	CDD:292891	17/54 (31%)
		SF1_like-KH	61..180	CDD:239088	76/121 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..292		35/128 (27%)
		Sam68-YY	<281..>306	CDD:293176	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590097
Domainoid	1	1.000	87	1.000	Domainoid score	I7974
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3866
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1163
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.860