DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qkr54B and qkia

DIOPT Version :9

Sequence 1:	NP_001261050.1	Gene:	qkr54B / 36966	FlyBaseID:	FBgn0022987	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_571299.1	Gene:	qkia / 30471	ZFINID:	ZDB-GENE-990415-230	Length:	383	Species:	Danio rerio

Alignment Length:	363	Identity:	100/363 - (27%)
Similarity:	158/363 - (43%)	Gaps:	80/363 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 GNVQINEK---ANEYIRDCMAERNRMDRK------FPIAEKLLEGEIEKVQTTGRIPSREQKYAD 112
            |.:::.|:   :.:|:...:.|:..|...      |...|:||:.||.:|        |:..|.|
Zfish     4 GEMEVKERPRPSPDYLMQLLNEKKLMTSLPNLCGIFTHLERLLDEEINRV--------RKDMYND 60

  Fly   113 ----IYREKPL----------RISQRVLVPIREHPKFNFVGKLLGPKGNSLRRLQEETLCKMTVL 163
                :..:.||          .:.:::.||::|:|.:||||::|||:|.:.::|:.||.||:.|.
Zfish    61 SVNGLVDKHPLELPEPVGPIVHLQEKLFVPVKEYPDYNFVGRILGPRGLTAKQLEAETGCKIMVR 125

  Fly   164 GRNSMRDRVKEEELRSSKDPKYAHLNSDLHVEISTIAPPAEAYARIAYAMAELRKYLIP--DSND 226
            ||:||||:.|||:.|..  |.:.|||.||||.|:.......|..::..|:.|::|.|:|  :..|
Zfish   126 GRSSMRDKKKEEQNRGK--PNWEHLNEDLHVLITVEDTQTRAEIKMRRAVEEVKKLLVPAAEGED 188

  Fly   227 IIRQEQLREL--MDSTSLNDNDNAK----SGYKKTSHMQGGNNVLGGGSINPIGGVKNTPHHSYR 285
            .:::.||.||  ::.|..:.|..|.    |.....:..||...:..     |.|.|  .|..:.|
Zfish   189 NLKKMQLMELAILNGTYRDTNIKAPTLAFSLAAAAAAAQGPRLIAA-----PPGQV--LPPATLR 246

  Fly   286 SSQPSSFS-KNVLAPKQKVMSILEKARTAMDETYGRGYDDGLGYDPHQSYDSYSYG--------- 340
            ...|:... .|::.|.|....:.....|.:..|    .|.|:.|.  ..|| |.|.
Zfish   247 PPTPAGTPIMNIIRPTQMATVLPNGTPTLVPPT----PDAGIIYT--TPYD-YPYALAPTSLLEY 304

  Fly   341 --TH-----------GHGPHGPPANILGGV--GGISGG 363
              .|           |..|.|.|.....||  |||..|
Zfish   305 PIEHSGVLGKRAWGLGTSPFGVPQEGTPGVFYGGILDG 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qkr54B	NP_001261050.1	Qua1	68..117	CDD:292891	13/58 (22%)
qkr54B	NP_001261050.1	SF1_like-KH	122..237	CDD:239088	48/118 (41%)
qkia	NP_571299.1	STAR_dimer	11..69	CDD:293152	13/65 (20%)
		SF1_like-KH	84..206	CDD:239088	49/123 (40%)
		Quaking_NLS	356..383	CDD:293159
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590105
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740