DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and LIMS3

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001381830.1	Gene:	LIMS3 / 96626	HGNCID:	30047	Length:	398	Species:	Homo sapiens

Alignment Length:	248	Identity:	69/248 - (27%)
Similarity:	105/248 - (42%)	Gaps:	43/248 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   581 QGRFASIPGIEDMN--MYPS----CAGMPEQFQQLRLHGDEASGK----NSTRTILCADCNQPIA 635
            :|.||....|.:.|  :|..    ||...:||.:...:  |..|:    :..:.:....|:|
Human    76 KGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFY--EFEGRKYCEHDFQMLFAPCCHQ--- 135

  Fly   636 MGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFC----GRDLAIRLKIPRCRAC 696
            .||..:.........:|||.||:|..|:|:|||:.:..:.|:..|    .|:.|..|....|:.|
Human   136 CGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKC 200

  Fly   697 ----DE--LIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRC 755
                ||  |||..:       .:|..||.|..|.:.|...   |.|......||.|:|::....|
Human   201 HAIIDEQPLIFKND-------PYHPDHFNCANCGKDLTAD---AQELKGELYCLPCHDKMGVPIC 255

  Fly   756 QRCKVAIGPADQGV--AWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFC 806
            ..|:   .|.:..|  |.|. .||...||||  :|.||.:|.|...::.:.:|
Human   256 GACR---RPIEGRVVNAMGK-QWHVEHFVCA--KCEKPFLGHRHYERKGLAYC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	18/60 (30%)
		LIM2_Testin_like	691..748	CDD:188727	18/62 (29%)
		LIM	755..810	CDD:295319	18/54 (33%)
LIMS3	NP_001381830.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900