DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and Tgfb1i1

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_006230411.1	Gene:	Tgfb1i1 / 84574	RGDID:	620173	Length:	473	Species:	Rattus norvegicus

Alignment Length:	426	Identity:	115/426 - (26%)
Similarity:	158/426 - (37%)	Gaps:	110/426 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   453 ASLAELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYDRLFR--SLHDKGISHDQCHLLQPM--- 512
            |.|::|.    .|.:.:..:|..|......::..|.|....:  |....|.|.|:.||...:
  Rat    18 ALLSDLE----TTTSHMSRLGAPKERPPETLTPPPPYGHQPQTGSGESSGASGDKDHLYSTVCKP 78

  Fly   513 ---KQV--------------HDWLLDDDQLLDEI--------DKVFAD-----MANG-------- 539
               |.|              .:.|.:.|:||.|:        |::.:.     ||.|
  Rat    79 RSPKSVAPVAPPFSSSSGVLGNGLCELDRLLQELNATQFNITDEIMSQFPSSKMAEGEGKEDQSE 143

  Fly   540 CKDI------SYPKPS-------LGELPTSQSSDSGFH-------SKPPTP--------GYGSED 576
            .|.|      ::|.||       ..||....:|.|.|.       |.||.|        |..|..
  Rat   144 DKSITTVPSSTFPAPSKPSATSATQELDRLMASLSDFRVQNHLPASGPPQPPAVSPTREGCPSPP 208

  Fly   577 LTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRLHGDEASGKNSTRTILCADCNQPIAMGEVAV 641
            ....:|...::.|:...::  |..|:|.|          |.|       ||..||:||| |:|..
  Rat   209 GQTNKGSLDTMLGLLQSDL--SRRGVPTQ----------AKG-------LCGSCNKPIA-GQVVT 253

  Fly   642 KADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYT 706
            ...|     ||||..|.|..|...|....:|...|..||......|.. |||..|::.|..|..|
  Rat   254 ALGR-----AWHPEHFLCRGCSTTLGGSSFFEKDGAPFCPECYFERFS-PRCGFCNQPIRHKMVT 312

  Fly   707 AAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGP-ADQGVA 770
            |. ...:|.:||||..|.||...:.:  .|:...|.|...:.:|||.|||.|:   || .|..::
  Rat   313 AL-GTHWHPEHFCCVSCGEPFGEEGF--HEREGRPYCRRDFLQLFAPRCQGCQ---GPILDNYIS 371

  Fly   771 WGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFC 806
            .....||..||||.  :|..|..||.|...|..|.|
  Rat   372 ALSALWHPDCFVCR--ECLAPFSGGSFFEHEGRPLC 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	21/56 (38%)
		LIM2_Testin_like	691..748	CDD:188727	19/56 (34%)
		LIM	755..810	CDD:295319	20/53 (38%)
Tgfb1i1	XP_006230411.1	Paxillin	<69..>118	CDD:281527	9/48 (19%)
		LIM1_Paxillin_like	240..292	CDD:259830	21/57 (37%)
		LIM2_Paxillin_like	299..350	CDD:188723	17/53 (32%)
		LIM3_Paxillin	358..410	CDD:188793	20/53 (38%)
		LIM4_Leupaxin	417..468	CDD:188796
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910