DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and prickle2a

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001071251.2	Gene:	prickle2a / 777736	ZFINID:	ZDB-GENE-061110-112	Length:	869	Species:	Danio rerio

Alignment Length:	221	Identity:	91/221 - (41%)
Similarity:	129/221 - (58%)	Gaps:	20/221 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   604 EQFQQLRLHGDEAS----GKNSTRTI-------LCADCNQPIAMGEVAVKADRAGKEIAWHPGCF 657
            |:.::|::..::..    |:.:.|.:       :|..|.:.|..|::||.|.|....:.|||.||
Zfish    92 EEKRELKIFSNQRKRDNLGRGTVRPLPLTITGAICQQCGEQIKGGDIAVFASRVAHGLCWHPHCF 156

  Fly   658 KCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQ 722
            .|..|.|||.||:||..:|:::|||..|.||| |||.||||:||..|.|.||...:|:||||||:
Zfish   157 VCGVCSELLVDLIYFQLEGKIYCGRHHAERLK-PRCSACDEIIFADECTEAEGQHWHMKHFCCYE 220

  Fly   723 CDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQG-VAWGDVHWHAS--CFVCA 784
            |:.||.||:||..|  ..|.|..|::.|:|..|..|...|| .||| :.:...||||:  ||.||
Zfish   221 CEAPLGGQRYIMRE--GHPHCCNCFENLYAEYCDSCGEHIG-IDQGQMTYEGQHWHATEDCFSCA 282

  Fly   785 GVQCSKPLIGGRFCVKENMPFCSPTC 810
              :||:.|:|..|..|:.:.:||..|
Zfish   283 --RCSQSLLGRPFLPKQGLIYCSRLC 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	26/56 (46%)
		LIM2_Testin_like	691..748	CDD:188727	31/56 (55%)
		LIM	755..810	CDD:295319	23/57 (40%)
prickle2a	NP_001071251.2	PET_Prickle	22..118	CDD:193602	4/25 (16%)
		LIM1_Prickle	126..184	CDD:188799	26/57 (46%)
		LIM2_Prickle	189..244	CDD:188802	31/56 (55%)
		LIM3_Prickle	249..307	CDD:188804	24/61 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11801
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820