DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and prickle1b

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001025269.1	Gene:	prickle1b / 556148	ZFINID:	ZDB-GENE-030131-2152	Length:	872	Species:	Danio rerio

Alignment Length:	317	Identity:	111/317 - (35%)
Similarity:	150/317 - (47%)	Gaps:	57/317 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   535 DM-ANGCKDISYPKPSLGELPTSQSSDSGFHSKPPT---PGYGSEDLTAGQGRFASIPGIEDMNM 595
            || :.|.|...:.:.|      :...|||...:..|   ||..:|.:   |..|:.:|  |:...
Zfish    26 DMDSRGAKAFGFQRSS------TSDDDSGCALEEYTWVPPGLRAEQV---QIYFSCLP--EEKVP 79

  Fly   596 YPSCAGMPEQFQQL-----------------------RLH------GDEASGKNSTRTI------ 625
            |.:..|...:.:||                       .||      ..||.|:.:.:.:
Zfish    80 YVNSPGEKHRIRQLLYQLPPHDNEIRYCQSLSDEERRELHMFSMQRKKEALGRGTPKLLPRALQH 144

  Fly   626 LCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKI 690
            .|..|.:.|..||:||.|.|||....|||.||.|.||.|||.||:||:|.|.:.|||..|..||
Zfish   145 NCEHCKENINGGEMAVFASRAGPGPCWHPACFTCYTCHELLVDLIYFYHNGNIHCGRHHAELLK- 208

  Fly   691 PRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRC 755
            |||.||||:||..|.|.||...:|:|||.|::|:..|.||:||.  |...|.|..|::.|:|..|
Zfish   209 PRCSACDEIIFADECTEAEGRHWHMKHFSCFECETILGGQRYIM--KDGRPFCCGCFESLYAEYC 271

  Fly   756 QRCKVAIGPADQGVAWGDVHWHAS--CFVCAGVQCSKPLIGGRFCVKENMPFCSPTC 810
            :.|...||.....:.:..|||||:  ||.||  ||...|:|..|..|:...:||..|
Zfish   272 EACGENIGVDHAQMTYEGVHWHATDKCFCCA--QCKTSLLGCPFLPKDGRIYCSKDC 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	31/56 (55%)
		LIM2_Testin_like	691..748	CDD:188727	28/56 (50%)
		LIM	755..810	CDD:295319	21/56 (38%)
prickle1b	NP_001025269.1	PET_Prickle	43..139	CDD:193602	20/100 (20%)
		LIM1_Prickle	146..204	CDD:188799	31/57 (54%)
		LIM2_Prickle	209..264	CDD:188802	28/56 (50%)
		LIM3_Prickle	269..327	CDD:188804	22/60 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750