DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and lims2

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_021334342.1	Gene:	lims2 / 553696	ZFINID:	ZDB-GENE-050522-56	Length:	378	Species:	Danio rerio

Alignment Length:	225	Identity:	64/225 - (28%)
Similarity:	93/225 - (41%)	Gaps:	31/225 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 YPSCAGMPEQFQQLRLHG--DEASGK----NSTRTILCADCNQPIAMGEVAVKADRAGKEIAWHP 654
            :..|....:.|||| :.|  .|..|:    :..:.:....|:|   .||..|.........:|||
Zfish    79 HEQCFTCAQCFQQL-IQGLFYEFEGRKYCEHDFQMLFAPCCHQ---CGEFVVGRVIKAMNSSWHP 139

  Fly   655 GCFKCITCRELLADLVYFFHQGQVFC----GRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHI 715
            .||.|..|..:|||:.:....|:..|    .|..|:.|....|:.|  |...:|........:|.
Zfish   140 DCFCCEVCEAVLADVGFVKSGGRPLCRSCHSRQKALSLGKHVCQKC--LCVVEEPLMYRSDPYHP 202

  Fly   716 KHFCCYQCDEPLAGQQYIAD--EKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQGV--AWGDVHW 776
            .||.|..|     |::..||  |......||.|:|:|....|..|:   .|.:..|  |.|. .|
Zfish   203 DHFNCSHC-----GKELTADARELKGELYCLPCHDKLGVPICGACR---RPVEGRVVNAMGK-QW 258

  Fly   777 HASCFVCAGVQCSKPLIGGRFCVKENMPFC 806
            |...|||  |:|.||.:|.|...::.:.:|
Zfish   259 HVEHFVC--VKCEKPFLGHRHYERKGLAYC 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	18/60 (30%)
		LIM2_Testin_like	691..748	CDD:188727	16/58 (28%)
		LIM	755..810	CDD:295319	18/54 (33%)
lims2	XP_021334342.1	LIM1_PINCH	57..115	CDD:188717	8/36 (22%)
		LIM2_PINCH	118..169	CDD:188718	17/53 (32%)
		LIM3_PINCH	182..231	CDD:188719	15/55 (27%)
		LIM4_PINCH	237..290	CDD:188720	18/56 (32%)
		LIM5_PINCH	298..351	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810