DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and lmo7a

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_021334325.1	Gene:	lmo7a / 553341	ZFINID:	ZDB-GENE-030219-74	Length:	1893	Species:	Danio rerio

Alignment Length:	351	Identity:	66/351 - (18%)
Similarity:	122/351 - (34%)	Gaps:	113/351 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 KNPVQIRMGA----QMRQDTPMRRVKF-------GGVSTIVYDCGLPANTDYDRDPVFAQILQAE 425
            |||...|..|    ::.:.:.:..:|:       ||:|.:        |.||.::|:....|:.:
Zfish  1640 KNPQMQRKQAASELELERRSILNAMKYRNPERASGGLSEV--------NRDYQKEPLTQSELERQ 1696

  Fly   426 PLKHAFQEARAGRAPSSVVISNIPAPVASLAELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYD 490
            .:                           |.|:|        :..|:..|.:.::.:.|:.
Zfish  1697 QI---------------------------LQEMR--------KKTSLNTDNSWIRQSTSSV---- 1722

  Fly   491 RLFRSLHDKGISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLGELPT 555
                                |.|:..|..:...:.||.:|:              |:.|.....:
Zfish  1723 --------------------PAKEPIDLPIRRGESLDNLDE--------------PRSSWRSSWS 1753

  Fly   556 SQSSDSGF--HSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRL--HGDEA 616
            :.:|.|..  :|:|.:...||....||:...|::...:.|:........|....:.|.  .....
Zfish  1754 TSNSTSSIPDYSRPHSALSGSTLQPAGRPGSATMQASQSMSSLRQSTSTPANPPEPRAPQRNRSV 1818

  Fly   617 SGKNSTRTILCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCG 681
            ||:.     :|:.|:.|:..| .|:..:..|  :.:|..||||..||   :||      |....|
Zfish  1819 SGRK-----ICSFCDTPLGKG-AAMIIESLG--LCYHLTCFKCSDCR---SDL------GGSQAG 1866

  Fly   682 RDLAIRLKIPRCRACDELIFTKEYTA 707
            .::.||.:...|..|...:.|.:.||
Zfish  1867 AEVRIRNQQLYCNVCYMRLKTGQPTA 1892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	17/56 (30%)
		LIM2_Testin_like	691..748	CDD:188727	5/17 (29%)
		LIM	755..810	CDD:295319
lmo7a	XP_021334325.1	CH	17..128	CDD:237981
		DUF4757	239..>311	CDD:318215
		DUF4757	733..881	CDD:318215
		TOP2c	<809..1096	CDD:330395
		PDZ	1184..1245	CDD:238080
		Neuromodulin_N	<1396..1506	CDD:331332
		LIM	1824..1882	CDD:259829	20/69 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900