DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and prickle1

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_012814522.1	Gene:	prickle1 / 549693	XenbaseID:	XB-GENE-486941	Length:	871	Species:	Xenopus tropicalis

Alignment Length:	369	Identity:	116/369 - (31%)
Similarity:	168/369 - (45%)	Gaps:	73/369 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 NAPYYDRLFRSLHDKGISHDQC--HLLQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPK 547
            :||:|...:.|.. |.:|..:.  .|.:|:..|:..|        |:|:..:....||:..|
Frog     6 SAPWYCGTYNSPW-KSVSSPRAIDELERPITTVYMPL--------EMDQKISKHTFGCQRSS--- 58

  Fly   548 PSLGELPTSQSSDSGFHSKPPT---PGYGSEDLTAGQGRFASIPGIEDMNMYPSCAG-------- 601
                    :...|||...:..|   ||...|.:   |..||.:|  |....|.:..|
Frog    59 --------TSDDDSGCAMEEYTWVPPGLRPEQV---QLYFACLP--EAKVPYVNSVGEKCRIKQL 110

  Fly   602 ---MP--------------EQFQQLRLHG----DEASGKNSTRTI-------LCADCNQPIAMGE 638
               :|              |:.::|::..    .||.|:.:.:.:       :|..|.:.|..||
Frog   111 LYQLPPHDNEVRYCQSLSEEEKKELQMFSAQRKKEALGRGNIKMLSRAVMHAMCEKCGEKINGGE 175

  Fly   639 VAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTK 703
            :|:...|||..:.|||.||.|.||.|||.||:||:..|::.|||..|..|| |||.||||:||..
Frog   176 IAIFVSRAGPGVCWHPSCFVCSTCNELLVDLIYFYQDGKIHCGRHHAELLK-PRCSACDEIIFAD 239

  Fly   704 EYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQG 768
            |.|.||...:|:.||.||:|:..|.||:||.  |...|.|..|::..:|..|:.|...||.....
Frog   240 ECTEAEGRHWHMNHFSCYECETVLGGQRYIM--KDGRPFCCGCFESHYAEYCESCGEHIGVDHAQ 302

  Fly   769 VAWGDVHWHA--SCFVCAGVQCSKPLIGGRFCVKENMPFCSPTC 810
            :.:...||||  :||.||  ||...|:|..|..|:...:||..|
Frog   303 MTYDGQHWHATETCFSCA--QCKVSLLGCPFLPKKGRIYCSKAC 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	28/56 (50%)
		LIM2_Testin_like	691..748	CDD:188727	28/56 (50%)
		LIM	755..810	CDD:295319	20/56 (36%)
prickle1	XP_012814522.1	PET_Prickle	60..156	CDD:193602	20/100 (20%)
		LIM1_Prickle	164..222	CDD:188799	28/57 (49%)
		LIM2_Prickle	227..282	CDD:188802	28/56 (50%)
		LIM3_Prickle	287..345	CDD:188804	21/60 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920