DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and Prickle4

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001277266.1	Gene:	Prickle4 / 381104	MGIID:	2685785	Length:	369	Species:	Mus musculus

Alignment Length:	292	Identity:	88/292 - (30%)
Similarity:	125/292 - (42%)	Gaps:	70/292 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 QVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLT 578
            |..||.|..|      :.:|.:          |.|     |....||||   :.|...|  ||.:
Mouse     4 QNSDWSLQQD------NPIFRE----------PDP-----PVYTDSDSG---RRPVEDY--EDTS 42

  Fly   579 AGQGRFASI-PGIEDMNMYPSCAG-------MP--------------EQFQQLRL----HGDEAS 617
            |.....:|: |...|:|...:..|       :|              |:..||||    ...::.
Mouse    43 AQAATCSSLGPPCLDINQVSNWPGFRTLLQQLPPQDSDERYCLALGEEELAQLRLFCAQRKQKSL 107

  Fly   618 GKNSTRTI-------LCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQ 675
            |:...|.:       .|..|.:.:..||..|.|.|||::..||..||.|..|.:.|.:|:||:|:
Mouse   108 GQGVARLLPPKLEGYTCKKCKKLLDPGEYGVFAARAGEQSCWHRPCFACQACGQGLINLIYFYHE 172

  Fly   676 GQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNM 740
            |.::|||..|..|: |||.|||:|||::..|.||...:|..||||..|..||.|.:|.....|
Mouse   173 GHLYCGRHHAELLR-PRCPACDQLIFSQRCTEAEGQRWHENHFCCQDCAGPLDGGRYALPGGS-- 234

  Fly   741 PLCLLCYDRLFAVRCQRCKVAIGPADQGVAWG 772
            |.|..|:.:.:.        :.|.:..|||.|
Mouse   235 PCCPSCFSKRYR--------SAGSSSVGVAEG 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	24/56 (43%)
		LIM2_Testin_like	691..748	CDD:188727	26/56 (46%)
		LIM	755..810	CDD:295319	5/18 (28%)
Prickle4	NP_001277266.1	PET_OEBT	1..116	CDD:193603	31/137 (23%)
		LIM1_Testin_like	124..181	CDD:188726	24/56 (43%)
		LIM2_Testin_like	187..241	CDD:188727	25/55 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810