DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tes and scel

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_005168027.1	Gene:	scel / 368684	ZFINID:	ZDB-GENE-030616-15	Length:	612	Species:	Danio rerio

Alignment Length:	551	Identity:	103/551 - (18%)
Similarity:	171/551 - (31%)	Gaps:	119/551 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 DRLNHAQVEHVAPALMPTQEAQQTWQSLGLMPVADDTLNEL---LANPKVAQALASPASAHPKLL 259
            |:.:..:.:.......|....|...:..|   .:.|.|||.   |..|.| ::|...::......
Zfish    74 DKTSKTETKTTTVTTSPGSSVQALSKRFG---GSQDKLNETRTPLNKPSV-KSLPRTSTTSTTTT 134

  Fly   260 VAFSEPLCESTAQFEENGALRAQTREKLLGISKPALLSLVTHGIVYDKVLGILQEKKLNISRDPK 324
            |.......|:|....:...:::.|:.:.:....||..|....|   |......::..:..|:|..
Zfish   135 VKNGTKTTETTVTTTKQDVVKSSTKLETVNDRNPADSSTRRTG---DYKTTRQEDITVKSSKDTV 196

  Fly   325 LGPIAEFR-----KEYVNNPQFRAEINTICPQPP-----MTPIKSPPGTPFNSPL-PLKNPVQIR 378
            .||.:..:     |.|.......|:......|..     :||..|...|.....: ..|..|...
Zfish   197 DGPSSPVKTTTSIKSYTKEDVLPAKTTPYSVQSTKSSENLTPTSSIMTTNTKPEISDSKTEVVTV 261

  Fly   379 MGAQMRQDTPMRRVK-FGGVSTIVYDCGLPANTDYDRDPVFAQILQAEPLKHAFQEARAGRAPSS 442
            ..::...|||...|| ...:.|...:.....||.....||..........|.....|::....:.
Zfish   262 KSSKTIIDTPASPVKTTTSIKTYTKEDVTSTNTKRPTSPVKTTTSIKTFTKEDVSPAKSTTTTTY 326

  Fly   443 VVISNIPAPVASLAELRGLNPATRAQLQSVGLDKNMLQSAVSN---APYYDRLFRSLHDKGISHD 504
            ...|:....||::...:.:.....:.:::....|...:..|::   .||..|..:|  .|...:|
Zfish   327 TTKSDYKTEVATVKSSKDIIDIPASPVKTTTSIKTYTKEDVTSPKTTPYSVRSTKS--SKDFLYD 389

  Fly   505 QCHLLQPMK-QVHDWLLDDDQLLDEIDKVFADMANGCKDI-----------------SYPKPSLG 551
                 .|.| .:.|:            |......|..|||                 ||.|..:.
Zfish   390 -----TPTKTSISDY------------KTEVVTVNSSKDIVDIPTSPVKTTTSYSIKSYTKEDVS 437

  Fly   552 ELPTSQSSDS---------------------GFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMN- 594
              ||..:|||                     ..:|||.:   ..|||::.: ...::....|.|
Zfish   438 --PTKTTSDSIRSTKSSEDLLYDTLIPLSIKSTNSKPDS---SREDLSSSK-TVRTVYSTIDRNE 496

  Fly   595 ----MYPS------CAGMPEQFQQLRLHGDEASGKNSTRTI-----------LCADCNQPIAMGE 638
                :.||      ....|.::.     .|..:.|.:|...           :|..|||.:...|
Zfish   497 WSTDLSPSYTRTSYTESRPFEYM-----SDSLTSKTTTTVYSSPERKVNAKDICTYCNQSMYTDE 556

  Fly   639 VAVKADRAGKEIAWHPGCFKCITCRELLADL 669
            ..:..|   ..|..|..||||..|...|.:|
Zfish   557 KFILDD---MNINCHARCFKCGVCNTSLGNL 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	15/43 (35%)
		LIM2_Testin_like	691..748	CDD:188727
		LIM	755..810	CDD:295319
scel	XP_005168027.1	LIM	544..>583	CDD:214528	14/41 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900