DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tes and jub

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster

Alignment Length:	783	Identity:	154/783 - (19%)
Similarity:	233/783 - (29%)	Gaps:	274/783 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 QHVCPDDDDATGWAQFEILGQI-----RAKP-------AYIKIKALASQPVQLEWVPPNAAPDVV 124
            |.:.|...... :...|..||.     ||:|       :.|....|..||::.........|:
  Fly   134 QRIAPQKHSPV-YENLEFYGQFDSNHKRAQPQSPGSRQSAILNGYLLMQPIRAGRFAHTPVPE-- 195

  Fly   125 TDYMEKLGTAQI-----PVAGSDAALKRKMQLELQVPPHDLDAALCDGLTETEAIQLQQYVQKLR 184
            ......|||.:.     |.:|..|||.....||....|
  Fly   196 NQGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAP--------------------------- 233

  Fly   185 EQCVGQGVVVRLGDRLNHAQVEHVAPALMPTQEAQQTWQSLGLMPVADDTLNELLANPKVAQALA 249
               :.:.::...|.|   ||.:.........||.|.|..|.|....|...||.|||:|...::::
  Fly   234 ---IYENIIPHSGQR---AQPQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMHQRSIS 292

  Fly   250 SPASAHPKLLVAFSEPLCESTAQFEENGALRAQTREKLLGISKPALLSLVTHGIVYDKVLGILQE 314
            |                  :||.....|:...:.|.          |||.:|
  Fly   293 S------------------NTASSSSLGSPTQRYRN----------LSLPSH------------- 316

  Fly   315 KKLNISRDPKLGPIAEFRKEYVNNPQFRAEINTICPQPPMTPIKSPPGTPFNSPLP-----LKNP 374
                :|..|....:|:.::.                    ||:|||.|....|..|     :.:.
  Fly   317 ----LSPVPTAQSVAKLQQH--------------------TPVKSPGGAINVSVNPNYIEDINSS 357

  Fly   375 VQIRMGAQMRQDTPMRRVKFGGVSTIVYDCGLPANTDYDRDPVFAQIL-----QAEPLKHAFQEA 434
            ..:.|.|.:.::|..........:|     |.||.......|:....|     .|.|       .
  Fly   358 DYVCMTANLHRNTAAGLATGRAAAT-----GAPAQRTVQEPPIITSSLAMGMATAAP-------P 410

  Fly   435 RAGRAPSSVVISNIPAPVASLAELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYDRLFRSLHDK 499
            ....||:|...:  ||...|.|.||....|..|.|            ||:.:|        ...:
  Fly   411 TTSNAPTSAAAA--PAAPTSTASLRATPIAMTAPL------------AVATSP--------TPSQ 453

  Fly   500 GISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLG----ELPTSQSSD 560
            |.:.....|                                      ||..|    .||.|.:
  Fly   454 GSTAVNAAL--------------------------------------KPRRGLTKNLLPYSVT-- 478

  Fly   561 SGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRLHGDEASGKNSTRTI 625
                  ||.|...:|    .|.:      ||::...     :.|:.:|...||:...
  Fly   479 ------PPRPAGPTE----AQRK------IEELTRQ-----LEEEIEQSEEHGEYFG-------- 514

  Fly   626 LCADCNQPI--------AMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGR 682
            :|..|.:.:        |||.:            :|..||.|.:|...|....::...|:|:|..
  Fly   515 ICHTCGEKVKGAGQACQAMGNL------------YHTNCFICCSCGRALRGKAFYNVHGRVYCEE 567

  Fly   683 DL---AIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCL 744
            |.   ..:....:|..|..||. :....|...::|...|.|..|:|.|.|..:..|....: .|:
  Fly   568 DYMYSGFQQTAEKCAICGHLIM-EMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKI-YCV 630

  Fly   745 LCYDRLFAVRCQRCKVAIGPAD-----QGVAWGDVHWHASCFVC--AGVQCSK-------PLIGG 795
            ..|.|:||.:|..|...|.|.:     ..|...|..:|..|::|  .|:|.:.       ||.|.
  Fly   631 NDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGR 695

  Fly   796 RFC 798
            ..|
  Fly   696 LLC 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604	12/91 (13%)
		LIM1_Testin_like	627..684	CDD:188726	14/64 (22%)
		LIM2_Testin_like	691..748	CDD:188727	14/56 (25%)
		LIM	755..810	CDD:295319	15/58 (26%)
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	14/64 (22%)
		LIM2_Ajuba_like	581..633	CDD:188741	14/53 (26%)
		LIM3_Ajuba_like	641..702	CDD:188822	15/58 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810