DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tes and Tesl

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001107222.1	Gene:	Tesl / 316142	RGDID:	1305365	Length:	406	Species:	Rattus norvegicus

Alignment Length:	803	Identity:	157/803 - (19%)
Similarity:	232/803 - (28%)	Gaps:	422/803 - (52%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LGHEAGAGAPCAECKDKCPGLDLHFWRKVCRNCKCPKIQH--VCPDDDDATGWAQFE------IL 90
            |||:.|.||||.:||:||.|.:||||||:||||||.:..|  :..:|:|......||      |:
  Rat     3 LGHKPGLGAPCLKCKEKCAGFELHFWRKICRNCKCGQEDHDILLSNDEDQKVGRLFEHTEYTNII 67

  Fly    91 GQIRAK--PAYIKIKALASQPV----------QLEWVPPNAAPDVVTDYMEKLGTAQIPVAGSDA 143
            .:::::  |.:.......:.|.          ..||.||....::..:||.|   .::.::||.|
  Rat    68 TKLKSEGMPMFKHNVMAMTNPCTAEKKFFNTGSYEWAPPVQRQELARNYMAK---EKLSLSGSWA 129

  Fly   144 ALKRKMQLELQVPPHDLDAALCDGLTETEAIQLQQYVQKLREQCVGQGVVVRLGDRLNHAQVEHV 208
            ....|.||..|:|.||.|.:.|..|:..|..:::|:::|.:.:.:|.|.:..|
  Rat   130 TQYLKKQLSKQLPAHDQDPSKCHELSPNEVREMEQFIKKYKNEALGVGAMKHL------------ 182

  Fly   209 APALMPTQEAQQTWQSLGLMPVADDTLNELLANPKVAQALASPASAHPKLLVAFSEPLCESTAQF 273
                                                                          ::.
  Rat   183 --------------------------------------------------------------SEV 185

  Fly   274 EENGALRAQTREKLLGISKPALLSLVTHGIVYDKVLGILQEKKLNISRDPKLGPIAEFRKEYVNN 338
            .:.|                            |||
  Rat   186 NDQG----------------------------DKV------------------------------ 192

  Fly   339 PQFRAEINTICPQPPMTPIKSPPGTPFNSPLPLKNPVQIRMGAQMRQDTPMRRVKFGGVSTIVYD 403
                                             :||.::|
  Rat   193 ---------------------------------QNPARVR------------------------- 199

  Fly   404 CGLPANTDYDRDPVFAQILQAEPLKHAFQEARAGRAPSSVVISNIPAPVASLAELRGLNPATRAQ 468
                 ||
  Rat   200 -----NT---------------------------------------------------------- 201

  Fly   469 LQSVGLDKNMLQSAVSNAPYYDRLFRSLHDKGISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVF 533

  Rat   202 ----------------------------------------------------------------- 201

  Fly   534 ADMANGCKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPS 598
                                 ||..|.....::|....|.
  Rat   202 ---------------------TSALSSKEKSTEPKKTQYS------------------------- 220

  Fly   599 CAGMPEQFQQLRLHGDEASGKNSTRTILCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCR 663
                                        |..|.|||..|:.|:.|:|||....|||.||.|.||.
  Rat   221 ----------------------------CYCCKQPIKEGDTAIYAERAGYNKLWHPSCFICSTCG 257

  Fly   664 ELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLA 728
            |||..::||:..|:::|||......| |||..||||||:||||.||...:|:|||.|:.||:.||
  Rat   258 ELLVHMIYFWKNGKLYCGRHYCDSEK-PRCAGCDELIFSKEYTQAENQNWHLKHFSCFDCDKILA 321

  Fly   729 GQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQGVAWGDVHWHAS--CFVCAGVQCSKP 791
            |:.|:.  .::.|:|..||.:..||:||.|:..|.|..|.|.:.:..||||  ||:|:  .|.|.
  Rat   322 GKIYVM--VNDKPVCKPCYMKNHAVKCQECQSVIDPELQRVTYNNFSWHASSECFLCS--CCRKC 382

  Fly   792 LIGGRFCVKENMPFCSPTCVRSL 814
            |.|.:|.....:.|||..|.:.:
  Rat   383 LFGQKFMPVNGLVFCSMECKKMM 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604	25/96 (26%)
		LIM1_Testin_like	627..684	CDD:188726	28/56 (50%)
		LIM2_Testin_like	691..748	CDD:188727	29/56 (52%)
		LIM	755..810	CDD:295319	22/56 (39%)
Tesl	NP_001107222.1	PET_testin	101..183	CDD:193604	26/158 (16%)
		LIM1_Testin	221..278	CDD:188797	28/56 (50%)
		LIM2_Testin	284..339	CDD:188800	29/56 (52%)
		LIM	346..404	CDD:295319	23/59 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352519
Domainoid	1	1.000	49	1.000	Domainoid score	I11468
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2617
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	1	1.000	-	-		FOG0001604
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24211
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.860