DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and Lpxn

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_038964643.1	Gene:	Lpxn / 293783	RGDID:	1304981	Length:	398	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	87/359 - (24%)
Similarity:	127/359 - (35%)	Gaps:	109/359 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 W--LLDDDQLLDEIDKVFADMANGC------KDISYP-KPSLGELPTSQSSDSGFHSKPPTPGYG 573
            |  .|..|.||:|::         |      :|.|.| ...|.:.||.:|      ..|.||
  Rat    10 WATFLVPDALLEELE---------CCTLQDSEDYSNPVSCCLDQQPTQES------KLPQTP--- 56

  Fly   574 SEDLTAGQGRFASI-------PGIEDMNMY-----PSCAGMP------EQFQQLRLHGDEASGKN 620
              ...:.||..:.:       ..|::.|:|     |..:.:|      .|..:|..|.:|...|.
  Rat    57 --KTLSTQGNTSPLKVQLVYTTNIQEPNVYSEVQEPKQSVLPPKTSAAAQLDELMAHLNELQAKV 119

  Fly   621 STR-------------------TIL-------------------CADCNQPIAMGEVAVKADRAG 647
            |.:                   ::|                   ||.|.:||           ||
  Rat   120 SVKADASRKPLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPI-----------AG 173

  Fly   648 KEI-----AWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTA 707
            |.|     :|||..|.|..|:|.|....:|...|..:|.:|.. .|..|||..|...|..|..||
  Rat   174 KVIHALGQSWHPEHFVCTHCKEELGSSPFFERNGLAYCSKDYH-HLFSPRCAYCAAPITDKVLTA 237

  Fly   708 AEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQGVAWG 772
            ..: |:|.:||.|..|.|....:.:  .||...|.|...:..:|:.:|..|...:  .:..::..
  Rat   238 MNK-TWHPEHFFCSHCGEVFGAEGF--HEKDKKPYCRKDFLAMFSPKCGGCNRPV--LENYLSAM 297

  Fly   773 DVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFC 806
            :..||..||||.  .|......|.|...:..|||
  Rat   298 NTVWHPECFVCG--DCFSSFSSGSFFELDGRPFC 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	20/61 (33%)
		LIM2_Testin_like	691..748	CDD:188727	19/56 (34%)
		LIM	755..810	CDD:295319	14/52 (27%)
Lpxn	XP_038964643.1	LIM1_Leupaxin	162..216	CDD:188790	21/64 (33%)
		LIM	223..274	CDD:413332	17/53 (32%)
		LIM	282..334	CDD:413332	14/52 (27%)
		LIM4_Paxillin_like	341..392	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910