DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and pxl1

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_596112.1	Gene:	pxl1 / 2540856	PomBaseID:	SPBC4F6.12	Length:	438	Species:	Schizosaccharomyces pombe

Alignment Length:	543	Identity:	127/543 - (23%)
Similarity:	188/543 - (34%)	Gaps:	180/543 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   327 PIAEFRKEYVNNPQFRAEINTICPQPPMTPIKSPPGTPFN-SPLPLKNPVQIRM--------GAQ 382
            ||.|.       |:|...         :|..::.|.:|.: :..||.|.|:.|:        |.:
pombe     4 PIPEL-------PRFERR---------LTGPRAAPSSPVSTNGSPLNNLVRSRLSDGALNFTGGR 52

  Fly   383 MRQDTPMRRVKFGGVSTIVYDCGLPANTDYDRDPVFAQILQAEPLKHAFQEARAGRAPSSVVISN 447
            :....|...:|            .|.:....|:|...|           ...|.......:..||
pombe    53 IATPLPQPSLK------------TPESPLSKRNPTIKQ-----------NRVRFDLPDDELSRSN 94

  Fly   448 IPAPVASLAELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYDRLFRSLHDKGISH--------- 503
            :.:|..:|     |..|:.:...|  |.|.:|....|.|...|..|.|..::..||
pombe    95 VSSPEKTL-----LTSASTSTFDS--LKKELLPELPSLAYSDDDEFPSSPEELNSHVNYPDVRNV 152

  Fly   504 DQCHL-LQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLGELPTSQSSD------- 560
            ..||. |||       |:|.| .:::..|.||            ...|..||..:||.
pombe   153 YDCHTGLQP-------LVDHD-CIEDRQKTFA------------SKQLPTLPLQKSSKLSNRRPA 197

  Fly   561 -SGFHSKP-------PTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRLHGDEAS 617
             ..|||.|       |||                      .:..||.......||...|.....|
pombe   198 LHSFHSAPANSLYPLPTP----------------------TSQLPSNLSSNNLFQSDSLKPSMVS 240

  Fly   618 GKNSTRTIL--------CADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFH 674
            ...||:.:|        |..|...:..|.:   ...:||::  ||.||||.||.:.|..:.:::.
pombe   241 SHTSTKPVLYRGNSEKSCHSCGGSLRAGRI---ISASGKKL--HPQCFKCDTCSQNLEHVGFYYR 300

  Fly   675 QGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIK--------HFCCYQCDEPLAGQQ 731
            :|:.:|..|...:.. |||:.|.        |..|:...||.        |||. .|.|..
pombe   301 EGKFYCHLDYHEQFS-PRCKHCK--------TPIEDQAVHINNDWFHENHHFCA-GCSEVF---- 351

  Fly   732 YIADEKSNMPL--------CLLCYDRLFAVRCQRC-KVAIGPADQGVAWGDVHWHASCFVCAGVQ 787
                 ..|:|.        |..|||..:||:|::| |..:|.:.:|   .|..:|:.|:.|..
pombe   352 -----NVNIPCIYRDDLYWCQTCYDNKYAVKCKKCRKPILGISVKG---SDGEYHSQCWTCGA-- 406

  Fly   788 CSKPLIG--GRFCVKENMPFCSP 808
            |: .|:|  |.|.: ||.|.|.|
pombe   407 CN-ALLGDEGYFMI-ENTPICRP 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	16/56 (29%)
		LIM2_Testin_like	691..748	CDD:188727	17/72 (24%)
		LIM	755..810	CDD:295319	19/57 (33%)
pxl1	NP_596112.1	LIM	258..314	CDD:278823	17/60 (28%)
		LIM	318..370	CDD:259829	14/69 (20%)
		LIM	378..428	CDD:259829	19/57 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	2	1.910