DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and FHL3

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_004459.2	Gene:	FHL3 / 2275	HGNCID:	3704	Length:	280	Species:	Homo sapiens

Alignment Length:	201	Identity:	58/201 - (28%)
Similarity:	87/201 - (43%)	Gaps:	36/201 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   627 CADCNQPIAMGEVAVKADRAGKEIAW-----HPGCFKCITCRELLADLVYFFHQGQVFCGRDLAI 686
            ||:|.|.|.         ...:|:.:     |.|||:|..|:..|||..:.....::.| .|...
Human    40 CAECQQLIG---------HDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLC-NDCYC 94

  Fly   687 RLKIPRCRACDELIF----TKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCY 747
            .....:|.||.|.:.    ..||..   .|:|...|.|..|::||..:.::.|:.::  .|:.||
Human    95 SAFSSQCSACGETVMPGSRKLEYGG---QTWHEHCFLCSGCEQPLGSRSFVPDKGAH--YCVPCY 154

  Fly   748 DRLFAVRCQRCKVAIGPADQGVAWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFC------ 806
            :..||.||.||...:  ...||.:.|..||..|.||.|  |..||.|.:|..::..|:|
Human   155 ENKFAPRCARCSKTL--TQGGVTYRDQPWHRECLVCTG--CQTPLAGQQFTSRDEDPYCVACFGE 215

  Fly   807 --SPTC 810
              :|.|
Human   216 LFAPKC 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	16/61 (26%)
		LIM2_Testin_like	691..748	CDD:188727	16/60 (27%)
		LIM	755..810	CDD:295319	20/62 (32%)
FHL3	NP_004459.2	LIM	<5..33	CDD:295319
		LIM1_FHL3	36..94	CDD:188807	17/63 (27%)
		LIM2_FHL3	98..155	CDD:188811	16/61 (26%)
		LIM3_FHL	162..213	CDD:188732	19/54 (35%)
		LIM4_FHL3	221..276	CDD:188818	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810