DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and FHL1

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_006724806.1	Gene:	FHL1 / 2273	HGNCID:	3702	Length:	339	Species:	Homo sapiens

Alignment Length:	195	Identity:	56/195 - (28%)
Similarity:	85/195 - (43%)	Gaps:	23/195 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   627 CADCNQPIAMGEVAVKADRAGKEI-----AWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAI 686
            |.:|.:||.       ||  .||:     .||..||:|..|...||:..:.....::.|.: ...
Human    56 CVECRKPIG-------AD--SKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK-CTT 110

  Fly   687 RLKIPRCRACDELIFTKEYTAAEEAT-FHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRL 750
            |...|:|:.|.:.|...:.....:.| :|...|.|..|.:.:....:.  .|.....|:.|::..
Human   111 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFF--PKGEDFYCVTCHETK 173

  Fly   751 FAVRCQRCKVAIGPADQGVAWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFCSPTCVRSLI 815
            ||..|.:|..||  ...|:.:.|..|||.||||  |.|||.|.|.||...|:..:| ..|.::.:
Human   174 FAKHCVKCNKAI--TSGGITYQDQPWHADCFVC--VTCSKKLAGQRFTAVEDQYYC-VDCYKNFV 233

Fly 816 815
Human 234 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	17/61 (28%)
		LIM2_Testin_like	691..748	CDD:188727	12/57 (21%)
		LIM	755..810	CDD:295319	23/54 (43%)
FHL1	XP_006724806.1	LIM	<21..49	CDD:413332
		LIM1_FHL1	56..109	CDD:188730	17/62 (27%)
		LIM2_FHL1	117..174	CDD:188808	11/58 (19%)
		LIM3_FHL1	178..230	CDD:188813	24/56 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810