DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and Lims2

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001366066.1	Gene:	Lims2 / 225341	MGIID:	2385067	Length:	341	Species:	Mus musculus

Alignment Length:	192	Identity:	61/192 - (31%)
Similarity:	84/192 - (43%)	Gaps:	34/192 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   627 CADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFC----GRDLAIR 687
            |..|.: ..:|.| :||..|.    ||||||:|..|...||||.:..:.|:..|    .|:.|..
Mouse    76 CGFCGE-FVIGRV-IKAMNAN----WHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 134

  Fly   688 LKIPRCRAC----DE--LIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLC 746
            |....|:.|    ||  |:|..:       .:|..||.|..|.:.|...   |.|......||.|
Mouse   135 LGKFICQRCHLAIDEQPLMFKND-------PYHPDHFSCSNCGKELTSD---ARELKGELYCLPC 189

  Fly   747 YDRLFAVRCQRCKVAIGPADQGV--AWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFC 806
            :|::....|..|:   .|.:..|  |.|. .||...||||  :|.||.:|.|...|:.:.:|
Mouse   190 HDKMGIPICGACR---RPIEGRVVNALGK-QWHVEHFVCA--KCEKPFLGHRHYEKKGLAYC 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	22/60 (37%)
		LIM2_Testin_like	691..748	CDD:188727	17/62 (27%)
		LIM	755..810	CDD:295319	19/54 (35%)
Lims2	NP_001366066.1	LIM1_PINCH	15..73	CDD:188717
		LIM2_PINCH	76..127	CDD:188718	21/56 (38%)
		LIM3_PINCH	140..190	CDD:188719	16/59 (27%)
		LIM4_PINCH	196..249	CDD:188720	19/56 (34%)
		LIM5_PINCH	257..310	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900