DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and pxl-1

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_001021185.2	Gene:	pxl-1 / 175831	WormBaseID:	WBGene00016197	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	393	Identity:	97/393 - (24%)
Similarity:	144/393 - (36%)	Gaps:	99/393 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   449 PAPVASLAELRGLNPA-TRAQL------------QSVGLDKNMLQSAVSN-----APYYDRLFRS 495
            ||..|.|::|:..... .||.:            ||..|..|:...:|||     :||..   ||
Worm    13 PALEALLSDLQHTTEVLRRAHISDRRSQSRDDFEQSYDLQGNLNTQSVSNGNITTSPYKR---RS 74

  Fly   496 LHDKGISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLGEL------P 554
            ...|..|..|       :::::   ::.:|...:               |.:||:..|      |
Worm    75 SEGKDYSKSQ-------ERIYE---NESRLNPPV---------------YSRPSVQSLLSQVEEP 114

  Fly   555 TSQSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRLHGDEASGK 619
            ..::|.|.....||:......|:.: .||..|...:...:|..:..|             |.|.|
Worm   115 PIRASSSRKSLGPPSQAQSYSDVRS-NGRSPSRDPLHSDSMIGTMNG-------------ELSSK 165

  Fly   620 NSTRTIL---CADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCG 681
            :...||.   ||.|.:|| :|:|.:   ..||  .|||..:.|..|...|....:|...|:.||.
Worm   166 HGVNTIPKGDCAACGKPI-IGQVVI---ALGK--MWHPEHYTCCECGAELGQRPFFERNGRAFCE 224

  Fly   682 RDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLC 746
            .|...:.. |:|:.|...| |....:.....|||:.|.|.:|::|.....:  .||:....|...
Worm   225 EDYHNQFS-PKCQGCHRAI-TDRCVSVMNKNFHIECFTCAECNQPFGEDGF--HEKNGQTYCKRD 285

  Fly   747 YDRLFAVRCQRCK--------VAIGPADQGVAWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENM 803
            :.||||.:|..|.        .|:|          .|||..||||.  .|.....|..|......
Worm   286 FFRLFAPKCNGCSQPITSNFITALG----------THWHPDCFVCQ--HCGVSFNGASFFEHNGA 338

  Fly   804 PFC 806
            |.|
Worm   339 PLC 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	19/56 (34%)
		LIM2_Testin_like	691..748	CDD:188727	15/56 (27%)
		LIM	755..810	CDD:295319	16/60 (27%)
pxl-1	NP_001021185.2	LIM1_Leupaxin	174..228	CDD:188790	20/59 (34%)
		LIM	235..290	CDD:278823	15/57 (26%)
		LIM3_Paxillin_like	294..346	CDD:188724	16/60 (27%)
		LIM4_Paxillin_like	353..404	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910