Protein Alignment Tes and PRICKLE2

DIOPT Version :9

• Sequence 1: NP_611215.1
• Gene: Tes / 36965
• FlyBaseID: FBgn0034223
• Length: 816
• Species: Drosophila melanogaster
• Sequence 2: XP_011531734.1
• Gene: PRICKLE2 / 166336
• HGNCID: 20340
• Length: 966
• Species: Homo sapiens
• Alignment Length: 794
• Identity: 145/794 - (18%)
• Similarity: 190/794 - (23%)
• Gaps: 475/794 - (59%)

  Fly    41 GAPCAECKDKCPGLDLHFWRKVCRNCKCPKIQH---VCP------------------DDDDATGW 84
            |.||..|.|:|||..||.|||:|.:||||:.:|   |.|                  ..||.:|.
Human    60 GQPCNACGDQCPGFALHKWRKICLHCKCPQEEHMVTVMPLEMEKTISKLMFDFQRNSTSDDDSGC 124

  Fly    85 AQFEILGQIRAKPAYIKIKALASQPVQLEWVPPNAAPDVVTDYMEKLGTAQIPVAGSDAALKRKM 149
            |..|                       ..||||...|:.|..|...|...::|...|.....|..
Human   125 ALEE-----------------------YAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIK 166

  Fly   150 QLELQVPPHDLDAALCDGLTETEAIQLQQYVQKLREQCVGQGVVVRLGDRLNHAQVEHVAPALMP 214
            ||..|:||||.:...|:.|.|.|..:|:.:..:.:.:.:|:|.|
Human   167 QLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNV--------------------- 210

  Fly   215 TQEAQQTWQSLGLMPVADDTLNELLANPKVAQALASPASAHPKLLVAFSEPLCESTAQFEENGAL 279
                                                                             
Human   211 ----------------------------------------------------------------- 210

  Fly   280 RAQTREKLLGISKPALLSLVTHGIVYDKVLGILQEKKLNISRDPKLGPIAEFRKEYVNNPQFRAE 344
                                                                             
Human   211 ----------------------------------------------------------------- 210

  Fly   345 INTICPQPPMTPIKSPPGTPFNSPLPLKNPVQIRMGAQMRQDTPMRRVKFGGVSTIVYDCGLPAN 409
                              .||        ||.: .||
Human   211 ------------------RPF--------PVTM-TGA---------------------------- 220

  Fly   410 TDYDRDPVFAQILQAEPLKHAFQEARAGRAPSSVVISNIPAPVASLAELRGLNPATRAQLQSVGL 474
                                                                             
Human   221 ----------------------------------------------------------------- 220

  Fly   475 DKNMLQSAVSNAPYYDRLFRSLHDKGISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVFADMANG 539
                                                                             
Human   221 ----------------------------------------------------------------- 220

  Fly   540 CKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPE 604
                                                                             
Human   221 ----------------------------------------------------------------- 220

  Fly   605 QFQQLRLHGDEASGKNSTRTILCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADL 669
                                 :|..|...|..|::||.|.|||..:.|||.||.|..|.|||.||
Human   221 ---------------------ICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDL 264

  Fly   670 VYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIA 734
            :||:..|:::|||..|..|| |||.||||:||..|.|.||...:|:|||||::|:..|.||:||.
Human   265 IYFYQDGKIYCGRHHAECLK-PRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIM 328

  Fly   735 DEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQG-VAWGDVHWHA--SCFVCAGVQCSKPLIGGR 796
              |...|.|..|::.|:|..|..|...|| .||| :.:...||||  :||.||  .|.|.|:|..
Human   329 --KEGRPYCCHCFESLYAEYCDTCAQHIG-IDQGQMTYDGQHWHATETCFCCA--HCKKSLLGRP 388

  Fly   797 FCVKENMPFCSPTC 810
            |..|:...|||..|
Human   389 FLPKQGQIFCSRAC 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604	26/86 (30%)
		LIM1_Testin_like	627..684	CDD:188726	28/56 (50%)
		LIM2_Testin_like	691..748	CDD:188727	29/56 (52%)
		LIM	755..810	CDD:295319	24/57 (42%)
PRICKLE2	XP_011531734.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11790
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D422310at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.820