DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tes and WTIP

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_011524754.1	Gene:	WTIP / 126374	HGNCID:	20964	Length:	472	Species:	Homo sapiens

Alignment Length:	309	Identity:	76/309 - (24%)
Similarity:	117/309 - (37%)	Gaps:	65/309 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   548 PSLGELPTSQSS-----DSGFHSK--PP--TPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMP 603
            ||:|...:|.||     .:|.::.  ||  .|........||...| .:|.:.   :.|...|.|
Human   135 PSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPF-PLPALP---LPPGREGGP 195

  Fly   604 EQFQQLRLHGDEASGKNSTRTI----------LCADCNQPI--------AMGEVAVKADRAGKEI 650
            ...:: ||   ||..:...|.:          :|..|...|        |||.:
Human   196 SAAER-RL---EALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSL----------- 245

  Fly   651 AWHPGCFKCITCRELLADLVYFFHQGQVFCGRDL---AIRLKIPRCRACDELIFTKEYTAAEEAT 712
             :|..||.|.:|...|....::....:|:|..|.   ..:....:|..|..||......|..: :
Human   246 -YHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGK-S 308

  Fly   713 FHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQG------VAW 771
            :|...|.|..|:|.|.|..:..|.::|: .|:..|..:||.:|..|...|.|| ||      |..
Human   309 YHPGCFRCSVCNECLDGVPFTVDVENNI-YCVRDYHTVFAPKCASCARPILPA-QGCETTIRVVS 371

  Fly   772 GDVHWHASCFVC------AGVQCSKPLIGGRFCVKENMPFCSPTCVRSL 814
            .|..:|.:|:.|      |.:..|.||.....|:::....|..:||..|
Human   372 MDRDYHVACYHCEDPGDEARMADSNPLAASLPCMEQLSLGCRSSCVPPL 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	14/64 (22%)
		LIM2_Testin_like	691..748	CDD:188727	15/56 (27%)
		LIM	755..810	CDD:295319	18/66 (27%)
WTIP	XP_011524754.1	LIM1_Ajuba_like	225..278	CDD:188738	14/64 (22%)
		LIM2_Ajuba_like	290..342	CDD:188741	15/53 (28%)
		LIM	350..404	CDD:295319	16/54 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810