DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tes and Lims1

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	XP_006513131.1	Gene:	Lims1 / 110829	MGIID:	1195263	Length:	398	Species:	Mus musculus

Alignment Length:	250	Identity:	70/250 - (28%)
Similarity:	107/250 - (42%)	Gaps:	47/250 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   581 QGRFASIPGIEDMN--MYPS----CAGMPEQFQQLRLHGDEASGK----NSTRTILCADCNQPIA 635
            :|.||....|.:.|  :|..    ||...:||.:...:  |..|:    :..:.:....|:|
Mouse    76 KGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFY--EFEGRKYCEHDFQMLFAPCCHQ--- 135

  Fly   636 MGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFC----GRDLAIRLKIPRCRAC 696
            .||..:.........:|||.||:|..|:|:|||:.:..:.|:..|    .|:.|..|....|:.|
Mouse   136 CGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKC 200

  Fly   697 ----DE--LIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIAD--EKSNMPLCLLCYDRLFAV 753
                ||  |||..:       .:|..||.|..|     |::..||  |......||.|:|::...
Mouse   201 HAIIDEQPLIFKND-------PYHPDHFNCANC-----GKELTADARELKGELYCLPCHDKMGVP 253

  Fly   754 RCQRCKVAIGPADQGV--AWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFC 806
            .|..|:   .|.:..|  |.|. .||...||||  :|.||.:|.|...::.:.:|
Mouse   254 ICGACR---RPIEGRVVNAMGK-QWHVEHFVCA--KCEKPFLGHRHYERKGLAYC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	18/60 (30%)
		LIM2_Testin_like	691..748	CDD:188727	19/64 (30%)
		LIM	755..810	CDD:295319	17/53 (32%)
Lims1	XP_006513131.1	LIM1_PINCH	72..130	CDD:188717	12/55 (22%)
		LIM2_PINCH	133..184	CDD:188718	17/53 (32%)
		LIM3_PINCH	197..247	CDD:188719	18/61 (30%)
		LIM4_PINCH	253..306	CDD:188720	17/55 (31%)
		LIM5_PINCH	314..367	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810