DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tes and Lpxn

DIOPT Version :9

Sequence 1:	NP_611215.1	Gene:	Tes / 36965	FlyBaseID:	FBgn0034223	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_598913.1	Gene:	Lpxn / 107321	MGIID:	2147677	Length:	386	Species:	Mus musculus

Alignment Length:	346	Identity:	82/346 - (23%)
Similarity:	118/346 - (34%)	Gaps:	95/346 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   523 DQLLDEIDK-VFADMANGCKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFAS 586
            |.||:|::: .|.|..      .|..|....|....:.:|.....|.|        .:.||..:.
Mouse     5 DALLEELERCTFQDSE------EYSNPVSCHLDQQSTEESKIPQTPKT--------LSSQGNTSP 55

  Fly   587 I-------PGIEDMNMY-----------PSCAGMPEQFQQLRLHGDEASGKNSTR---------- 623
            :       ..|::.|:|           |.......|..:|..|..|...|.|.:
Mouse    56 LKVQLVYATNIQEPNVYSEVQEPKESVLPPKTSAAAQLDELMAHLSEMQAKVSVKADTSRKPLPD 120

  Fly   624 -------------------------TI---LCADCNQPIAMGEVAVKADRAGKEI-----AWHPG 655
                                     |:   .||.|.:||           |||.|     :|||.
Mouse   121 QQDHKASLDSMLGDLEQELQDLGIATVPKGYCASCQKPI-----------AGKVIHALGQSWHPE 174

  Fly   656 CFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCC 720
            .|.|..|:|.|....:|...|..:|.:|.. ||..|||..|...|..|..||..: |:|.:||.|
Mouse   175 HFVCTHCKEELGSSPFFERSGLAYCSKDYH-RLFSPRCAYCAAPITDKVLTAMNK-TWHPEHFFC 237

  Fly   721 YQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQGVAWGDVHWHASCFVCAG 785
            ..|.|....:.:  .||...|.|...:..:|:.:|..|...:  .:..::..:..||..||||.
Mouse   238 SHCGEVFGAEGF--HEKDKKPYCRKDFLAMFSPKCGGCNRPV--LENYLSAMNTVWHPECFVCG- 297

  Fly   786 VQCSKPLIGGRFCVKENMPFC 806
             .|......|.|...:..|||
Mouse   298 -DCFSSFSSGSFFELDGRPFC 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tes	NP_611215.1	PET_testin	110..197	CDD:193604
		LIM1_Testin_like	627..684	CDD:188726	20/61 (33%)
		LIM2_Testin_like	691..748	CDD:188727	19/56 (34%)
		LIM	755..810	CDD:295319	14/52 (27%)
Lpxn	NP_598913.1	LD motif 1	3..15		4/9 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..52		7/46 (15%)
		LD motif 2	70..82		2/11 (18%)
		LD motif 3	92..103		3/10 (30%)
		LIM	150..204	CDD:295319	21/64 (33%)
		LIM	211..262	CDD:295319	17/53 (32%)
		LIM	270..322	CDD:295319	14/52 (27%)
		LIM4_Paxillin_like	329..380	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910