DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10764 and CG5246

DIOPT Version :9

Sequence 1:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	86/289 - (29%)
Similarity:	140/289 - (48%)	Gaps:	57/289 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRSLVSVALLSLLTLCVTE----------NEHFKFLETPCGISTRPKISGGDDAAEPNSIWMAAI 55
            |:.||.:::|.:|:.|..:          |.|...      :....::.||.|:....:.:..:|
  Fly     1 MKCLVLISVLVILSQCSAKSVKIHRRHQLNHHLGH------VKPETRVIGGVDSPTGFAPYQVSI 59

  Fly    56 FNS-SDFQCGGTIIHMRFVLSAAHC---------LVRGYDLYVRLGARNINEPAAVHTVINVFVH 110
            .|: .:..|||:||..:::|:||||         :|.|...|.|.||..:.:.:.:|      ..
  Fly    60 MNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTGTVDYTRPGAEYLVDGSKIH------CS 118

  Fly   111 HDFIASEYRNDIGLLQLSESIVYTVRVQPICIFLDPALKGSVEKLKTFRAL-GWGNRN--GKLSI 172
            ||..|  |.|||.|:..::.|||....|||.:    |.|||:.|:.....| |||:..  |:.|.
  Fly   119 HDKPA--YHNDIALIHTAKPIVYDDLTQPIKL----ASKGSLPKVGDKLTLTGWGSTKTWGRYST 177

  Fly   173 MLQTIYLLHLKRNECKRKL-NFN-LNSRQICAGTKNGD-TCRGDSGGPLSTNILFPSNKSYEVQL 234
            .||.|.|.::..:.|:.:: |.| |:...:|..|:.|: :|.||||||     |..:|::.   :
  Fly   178 QLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGDSGGP-----LVDANQTL---V 234

  Fly   235 GIVSFGDPECRGVG---VYTDVTSYVDWI 260
            |:|::|  |...:|   |:..|..|.|||
  Fly   235 GVVNWG--EACAIGYPDVFGSVAYYHDWI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	76/241 (32%)
		Tryp_SPc	38..263	CDD:238113	78/242 (32%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	76/241 (32%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	78/242 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437371
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940