DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10764 and CG18420

DIOPT Version :9

Sequence 1:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_995715.1	Gene:	CG18420 / 2768924	FlyBaseID:	FBgn0028866	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	89/271 - (32%)
Similarity:	136/271 - (50%)	Gaps:	23/271 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LVSVALLSLLTLCVTENEHF------KFLETPCG----ISTRPKISGGDDAAEPNSIWMAAIFNS 58
            :|.:.:.|:|.|...    |      :||::.||    :...|:|..|..|...:|.|||.:..|
  Fly     3 IVVIGMASILLLLTV----FPLLGSTQFLDSECGTRSPLKLGPRIVNGKVAVRNSSPWMAFLHTS 63

  Fly    59 SD-FQCGGTIIHMRFVLSAAHCLVRGYDLYVRLGA--RNINEPAAVHTVINVFVHHDFIASEYRN 120
            |: |.||||:|..|.||:||||.:....:.||||.  |.:......|.|...|.|..:..:.:.|
  Fly    64 SNQFICGGTLISRRLVLTAAHCFIPNTTIVVRLGEYNRKLKGYREEHQVNRTFQHRFYDPNTHAN 128

  Fly   121 DIGLLQLSESIVYTVRVQPICIFLDPALKGSVEKLKTFRALGWGNRNGKL-SIMLQTIYLLHLKR 184
            ||.||:|..::||...::||||..|.:.|..::.:|.....|||...... |..|:|   |.:.|
  Fly   129 DIALLRLVSNVVYKANIRPICIMWDASWKHHIDSIKVLTGTGWGRTESMHDSSELRT---LDISR 190

  Fly   185 NECKRKLNFNLNSRQICAGTKNGDTCRGDSGGPLSTNILFPSNKSYEVQLGIVSFGDPECRGVGV 249
            ...|.....::.|.|.|||..|.:.|.||:|||:...:.: .|....||:|| :..:..|:...|
  Fly   191 QPSKMCAFGSVLSNQFCAGNWNSNLCIGDTGGPVGAMVRY-RNAFRFVQVGI-AITNKRCQRPSV 253

  Fly   250 YTDVTSYVDWI 260
            :|||.|::::|
  Fly   254 FTDVMSHIEFI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	78/226 (35%)
		Tryp_SPc	38..263	CDD:238113	79/227 (35%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	78/226 (35%)
CG18420	NP_995715.1	Tryp_SPc	43..267	CDD:238113	79/227 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463428
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840