DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10764 and CG33458

DIOPT Version :9

Sequence 1:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_995854.2	Gene:	CG33458 / 2768846	FlyBaseID:	FBgn0053458	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	92/275 - (33%)
Similarity:	144/275 - (52%)	Gaps:	17/275 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALLSLLTLCVTENEHFKF-LETPCGISTRP-KISGGDDAAEPNSIWMAAIFNSSDFQCGGTIIHM 70
            |||:||.|....:..:.: ||..||||... :|:||.|:....:.|:|.:..:|.|.|||::::.
  Fly     6 ALLALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNH 70

  Fly    71 RFVLSAAHCL-VRGYDLYVRLGAR--------NINEPAAVH---TVINVFVHHDFIASEYRNDIG 123
            .|||:||||. .:...:.||||..        |.:|.||.|   .::...:|..:..:.| .||.
  Fly    71 WFVLTAAHCFRDKNAKVLVRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHY-YDIA 134

  Fly   124 LLQLSESIVYTVRVQPICIFLDPALKGSVEKLKTFRALGWGNRN-GKLSIMLQTIYLLHLKRNEC 187
            |.:|:..:|||..::|||:.|:|..:..|:.::.|...|||..| .::|..||...:..:.|..|
  Fly   135 LAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWGATNASEVSDKLQLTRIPQIDRFTC 199

  Fly   188 KRKLNFNLNSRQICAGTKNGDTCRGDSGGPLSTNILFPSNKSYEVQLGIVSFGDPECRGVGVYTD 252
            :....:.::...||||.......:|||||||.:.:.:...|.: .|.||||.......||.|:|:
  Fly   200 RYWFGYMVDRTHICAGESKHYVGKGDSGGPLGSMVDYKYAKRF-FQFGIVSHLRQPFHGVSVFTN 263

  Fly   253 VTSYVDWISSTIARN 267
            :.||.:||..||..|
  Fly   264 ILSYSNWIHRTIITN 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	75/235 (32%)
		Tryp_SPc	38..263	CDD:238113	77/237 (32%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
CG33458	NP_995854.2	Tryp_SPc	37..271	CDD:214473	75/235 (32%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	77/237 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810