DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10764 and CG30286

DIOPT Version :9

Sequence 1:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_726082.3	Gene:	CG30286 / 246529	FlyBaseID:	FBgn0050286	Length:	277	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	86/275 - (31%)
Similarity:	140/275 - (50%)	Gaps:	28/275 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLTLCVTENEH--FKFLETPCGISTRPKISGGDDAAE-PNSIWMAAIFNSSDFQCGGTIIHMRFV 73
            |||..:..:.|  .:|||..||..:...:...:..|. ..|.|||.:..|.:..||||:::.||:
  Fly     6 LLTSLLPWHPHATAQFLEPDCGYMSPEALQNEEHQAHISESPWMAYLHKSGELVCGGTLVNHRFI 70

  Fly    74 LSAAHCLVRGYDLYVRLGARN-----------INEPAAVHTVINVFVHHDFIASEYRNDIGLLQL 127
            |:||||:....:|.||||..|           ...|:....:...|.|..:..:...:|||||:|
  Fly    71 LTAAHCIREDENLTVRLGEFNSLTSIDCNGSDCLPPSEDFEIDVAFRHGGYSRTNRIHDIGLLRL 135

  Fly   128 SESIVYTVRVQPICIFLDPALKGSVEKLKTFRALGWGNRNGK-LSIMLQTIYLLHLKRNECKRKL 191
            ::|:.|.|.::|||:..:..|:..:|:|....|.|||....: .:.:|::|.:..:....|.:..
  Fly   136 AKSVEYKVHIKPICLITNTTLQPKIERLHRLVATGWGRSPSEAANHILKSIRVTRVNWGVCSKTY 200

  Fly   192 NFNLNSRQICAGTKNGDTCRGDSGGP------LSTNILFPSNKSYEVQLGIVSFGDPECRGVGVY 250
            ..:....|||...::|.:|.||||||      |...:||       ||:||||:|:.||....|:
  Fly   201 WVDRRRDQICVSHESGVSCSGDSGGPMGQAIRLDGRVLF-------VQVGIVSYGNAECLSPSVF 258

  Fly   251 TDVTSYVDWISSTIA 265
            |:|..::|||.:.::
  Fly   259 TNVMEHIDWIMAALS 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	75/241 (31%)
		Tryp_SPc	38..263	CDD:238113	77/243 (32%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
CG30286	NP_726082.3	Tryp_SPc	39..269	CDD:238113	76/236 (32%)
CG30286	NP_726082.3	Tryp_SPc	39..268	CDD:214473	75/235 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463414
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840