DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10764 and CG30088

DIOPT Version :9

Sequence 1:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	105/292 - (35%)
Similarity:	154/292 - (52%)	Gaps:	39/292 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SLVSVALLSLLTLCVTENEHF--KFLETPCGIS----TRPKISGGDDAAEPNSIWMAAIFNSSDF 61
            ||.|.::...:.:|:...|..  .||...||:|    ...:|..|.:|...::.:||.::.||:.
  Fly     4 SLASTSIYICMCVCLVLQEQVAANFLIPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEI 68

  Fly    62 QCGGTIIHMRFVLSAAHCLVRGYDLYVRLGARNI-----------NEPAAVHTVINVFVHHDFIA 115
            .||||||..|::|:||||: |.| |.||||..:|           :.||....::        :|
  Fly    69 HCGGTIISSRYILTAAHCM-RPY-LKVRLGEHDITRNPDCQGGSCSPPAEEFDIV--------LA 123

  Fly   116 SEYR-------NDIGLLQLSESIVYTVRVQPICIFLDPALKGSVEKLKTFRALGWGNRNGKLSI- 172
            ::|:       |||.||:||.:|.:.|.:||||:.|:||...:|.:   |:|.|||......|.
  Fly   124 TKYKRFDRFLANDIALLKLSRNIRFNVHIQPICLILNPAAAPNVHE---FQAFGWGQTETNHSAN 185

  Fly   173 MLQTIYLLHLKRNECKRKLNFNLNSRQICAGTKNGDTCRGDSGGPLSTNILFPSNKSYEVQLGIV 237
            :|||..|.......|:..|:..:...|:|.|.:..|||.|||||||.|.:.:.....| :|||||
  Fly   186 VLQTTVLTRYDNRHCRSVLSMPITINQLCVGFQGSDTCSGDSGGPLVTKVNYDGVWRY-LQLGIV 249

  Fly   238 SFGDPECRGVGVYTDVTSYVDWISSTIARNDY 269
            ||||.:|:..||||.|.:|:.||...:..|.|
  Fly   250 SFGDDKCQSPGVYTYVPNYIRWIRYVMQSNGY 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	91/241 (38%)
		Tryp_SPc	38..263	CDD:238113	93/243 (38%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	91/241 (38%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	92/241 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463393
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4848
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
	7	6.790