DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl3 and adgrl2a

DIOPT Version :9

Sequence 1:NP_001286526.1 Gene:mthl3 / 36961 FlyBaseID:FBgn0028956 Length:511 Species:Drosophila melanogaster
Sequence 2:XP_021335387.1 Gene:adgrl2a / 57987 ZFINID:ZDB-GENE-000607-49 Length:1520 Species:Danio rerio


Alignment Length:290 Identity:68/290 - (23%)
Similarity:115/290 - (39%) Gaps:65/290 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 VAIVISLICIILTISVYLYVEKLRN----LH-GKCFICYLASLFLGYFFLVLNVWKYSSGFCVTA 276
            |.||:||||:.::|..:.:...|::    :| ..|...::|.|.   |.:.:::.:......:.|
Zfish   869 VGIVVSLICLAMSIFTFCFFRGLQSDRNTIHKNLCINLFIAELI---FLIGIDMTEPKLACSIIA 930

  Fly   277 GFLGYFSVIAAFFWLSV----ISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAITY 337
            |.|.|| .:|:|.|:.:    :.|.|...|...             .|...|.:....||.|:..
Zfish   931 GILHYF-FLASFAWMCLEGVQLYLMLVEVFESE-------------YSRRKYFYMAGYLLPAVVV 981

  Fly   338 IADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEAQN 402
            .....|....    .|..|.||:.. |...:..|.||:..||:.|:...::|.:::||      :
Zfish   982 GVSAAVDFRS----YGTKKACWLRM-DNHFIWSFIGPVTFIIMLNLIFLLITMYKMMK------H 1035

  Fly   403 FTQQQKTTNRL-------------NSDKQTY---ALFLR--------LFIIMGLSWSLEIISFLL 443
            .|..:..::||             |||...|   ..|::        |..::||:||..:. |:.
Zfish  1036 STSLKPDSSRLEHINNYRVCDGYYNSDLPGYEDNKPFIKSWVMGGFALLCLLGLTWSFGLF-FIS 1099

  Fly   444 SKNQAWAKAFMVADYFNWSQGTVIFLLFVL 473
            ..:...|..|.:   ||..||..||....|
Zfish  1100 ESSVVLAYLFTI---FNTFQGMFIFTFHCL 1126

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl3NP_001286526.1 Methuselah_N 26..204 CDD:284145
7tm_4 216..436 CDD:304433 57/251 (23%)
adgrl2aXP_021335387.1 Gal_Lectin 61..141 CDD:307994
OLF 155..411 CDD:321983
HormR 482..545 CDD:214468
GAIN 555..776 CDD:318649
GPS 800..851 CDD:197639
7tm_GPCRs 860..1141 CDD:333717 68/290 (23%)
TM helix 1 863..887 CDD:320095 8/17 (47%)
TM helix 2 896..917 CDD:320095 5/23 (22%)
TM helix 3 927..949 CDD:320095 8/22 (36%)
TM helix 4 968..984 CDD:320095 4/15 (27%)
TM helix 5 1003..1026 CDD:320095 7/22 (32%)
TM helix 6 1074..1099 CDD:320095 6/25 (24%)
TM helix 7 1103..1128 CDD:320095 9/27 (33%)
Latrophilin 1140..1520 CDD:308136
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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