Protein Alignment mthl3 and adgrl2a

DIOPT Version :10

• Sequence 1: NP_663308.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_073772399.1
• Gene: adgrl2a / 57987
• ZFINID: ZDB-GENE-000607-49
• Length: 1500
• Species: Danio rerio
• Alignment Length: 278
• Identity: 65/278 - (23%)
• Similarity: 113/278 - (40%)
• Gaps: 56/278 - (20%)

  Fly   217 VAIVISLICIILTISVYLYVEKLRN----LH-GKCFICYLASLFLGYFFLVLNVWKYSSGFCVTA 276
            |.||:||||:.::|..:.:...|::    :| ..|...::|.|.   |.:.:::.:......:.|
Zfish   864 VGIVVSLICLAMSIFTFCFFRGLQSDRNTIHKNLCINLFIAELI---FLIGIDMTEPKLACSIIA 925

  Fly   277 GFLGYFSVIAAFFWLSV----ISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAITY 337
            |.|.|| .:|:|.|:.:    :.|.|...|...             .|...|.:....||.|:..
Zfish   926 GILHYF-FLASFAWMCLEGVQLYLMLVEVFESE-------------YSRRKYFYMAGYLLPAVVV 976

  Fly   338 IADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEAQN 402
            .....|....    .|..|.||:.. |...:..|.||:..||:.|:...::|.:::||      :
Zfish   977 GVSAAVDFRS----YGTKKACWLRM-DNHFIWSFIGPVTFIIMLNLIFLLITMYKMMK------H 1030

  Fly   403 FTQQQKTTNRLN----SDKQTYALFLR--------LFIIMGLSWSLEIISFLLSKNQAWAKAFMV 455
            .|..:..::||.    .|.:.   |::        |..::||:||..:. |:...:...|..|.:
Zfish  1031 STSLKPDSSRLEHINYEDNKP---FIKSWVMGGFALLCLLGLTWSFGLF-FISESSVVLAYLFTI 1091

  Fly   456 ADYFNWSQGTVIFLLFVL 473
               ||..||..||....|
Zfish  1092 ---FNTFQGMFIFTFHCL 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_663308.1	Methuselah_N	26..204	CDD:429053
		7tmB3_Methuselah-like	208..486	CDD:410632	65/278 (23%)
		TM helix 1	210..235	CDD:410632	8/17 (47%)
		TM helix 2	244..266	CDD:410632	4/21 (19%)
		TM helix 3	274..301	CDD:410632	10/30 (33%)
		TM helix 4	318..338	CDD:410632	5/19 (26%)
		TM helix 5	364..393	CDD:410632	8/28 (29%)
		TM helix 6	415..442	CDD:410632	7/34 (21%)
		TM helix 7	450..475	CDD:410632	9/24 (38%)
adgrl2a	XP_073772399.1	None