DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl3 and adgre10

DIOPT Version :9

Sequence 1:NP_001286526.1 Gene:mthl3 / 36961 FlyBaseID:FBgn0028956 Length:511 Species:Drosophila melanogaster
Sequence 2:XP_021333746.1 Gene:adgre10 / 569655 ZFINID:ZDB-GENE-090313-152 Length:690 Species:Danio rerio


Alignment Length:292 Identity:62/292 - (21%)
Similarity:120/292 - (41%) Gaps:62/292 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 VISLICII----------LTISVYLYVEKLRNLHGKCFICYLASLFLGYFFLV-----LNVWKYS 269
            :::|:|:|          |:.::..:...:.|: .:..||  .||...:..|:     |::.:..
Zfish   415 LLNLVCVIVGLVFFSLALLSFALCQWSPGVNNV-ARINIC--ISLLSAHLLLLLTQQFLSLIRPQ 476

  Fly   270 SGFCVTAGFLGYFSVIAAFFWLSVISLTLW---NSFSGNSSWLNRFLPQNRFLSYNLYAWGMALL 331
            ...||....|.:|..::||.|:.:.::.|:   .:.|..||.....| .|.||....|...:..:
Zfish   477 QVLCVVIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQVSSRKKEVL-SNGFLCVIGYVVALIGV 540

  Fly   332 LTAITYIADQVVKNEKLRPRVGVG-KNCWIYTGDMTVMIYFYGPMLLIIVFNITMFVLTAFRIMK 395
            ..:|..:.:            |.| :.|||.. |......|.||:.:|:..|:.:|:..:..:..
Zfish   541 SVSIGMVPE------------GYGSEQCWIKM-DKGFFWSFLGPVCVILGLNVILFISISIYLNS 592

  Fly   396 VKKEAQNFTQQQKTTNRLNSD----KQTYALFLRL---FIIMGLSWSLEIISFLLSKNQAWAKAF 453
            ..|             :||::    |||..:..:.   |:|:|..|   |:.|....|......|
Zfish   593 ALK-------------KLNAEVSQLKQTKVMVFKTLGQFVILGCPW---ILGFFAHVNMVVEIVF 641

  Fly   454 MVADYFNWSQGTVIFLLFVLRPSTLKLLKERI 485
            ::   .|..|||.|||::.:..:.::...::|
Zfish   642 II---INSQQGTFIFLIYCVLSTEIRQQYKKI 670

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl3NP_001286526.1 Methuselah_N 26..204 CDD:284145
7tm_4 216..436 CDD:304433 50/241 (21%)
adgre10XP_021333746.1 GPS 360..406 CDD:197639
7tm_GPCRs 413..672 CDD:333717 62/292 (21%)
TM helix 1 413..437 CDD:320095 4/21 (19%)
TM helix 2 446..467 CDD:320095 6/23 (26%)
TM helix 3 481..503 CDD:320095 6/21 (29%)
TM helix 4 527..543 CDD:320095 3/15 (20%)
TM helix 5 561..584 CDD:320095 6/22 (27%)
TM helix 6 608..631 CDD:320095 6/25 (24%)
TM helix 7 635..660 CDD:320095 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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