Protein Alignment mthl3 and adgrf6

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_021324327.1
• Gene: adgrf6 / 565101
• ZFINID: ZDB-GENE-041001-212
• Length: 11675
• Species: Danio rerio
• Alignment Length: 373
• Identity: 74/373 - (19%)
• Similarity: 134/373 - (35%)
• Gaps: 103/373 - (27%)

  Fly   152 YFLNHELPGNEFTLFENGSLLRHWDKVELSKREY-------------CVQHLSFKDDSIRIAPHF 203
            |.||:|..|....:|.|.: |..||......:.|             |....||   |:.::|..
Zfish 11282 YGLNNETLGIPQCVFWNFN-LSVWDSYGCEAKPYISNGNETDIITCECNHTTSF---SMLMSPFS 11342

  Fly   204 CPLSSEHSRTWKTVAIVISLICIILTISVYLYVEKLRN------------------LHGKCFI-- 248
            .........|:..|||.::.:.:.:.|...::....||                  :...|||
Zfish 11343 IDNKVLDYITYIGVAISMASLILCIIIEAIVWRSTTRNDTSYMRHVSIVNIAISLLIADVCFIIG 11407

  Fly   249 -------------CYLASLFLGYFFLVLNVWKYSSGFCVTAGFLGYFSVIAAFFWLSVISLTLWN 300
                         |.....|:.:|:|||                        |||:.:.:|.|..
Zfish 11408 AAISKEQPTPADRCSSVVFFMHFFYLVL------------------------FFWMLISALLLLY 11448

  Fly   301 SFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAITYIADQVVKNEKLRPRVGVGKN-CWIYTGD 364
            ......|.::|.  :...::::: ::|..||::.||..:       ...|:|.|.|. ||:...:
Zfish 11449 RTIMVLSHMSRV--KMMIIAFSV-SYGAPLLISVITVAS-------TAGPQVYVSKQACWLNWNE 11503

  Fly   365 MTVMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEAQNFTQQQKTTNRLNSDKQTYALFLR---- 425
            ...::.|..|.|.|:..|:.:.::...:::  ::...:.||.        .:|.|..:.:|
Zfish 11504 SKALLAFVIPALTIVAINLVVLIVVLSKLL--RRGVGDATQP--------DEKHTLMVIVRCVAF 11558

  Fly   426 LFIIMGLSWSLEIISFLLSKNQAWAKAFMVADYFNWSQGTVIFLLFVL 473
            |..|.||:|... |..::|:...   ..:|....|..||..|.:..||
Zfish 11559 LTPIFGLTWGFG-IGTMVSRELG---VHVVFALLNSLQGFFILVFGVL 11602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	16/64 (25%)
		7tm_4	216..436	CDD:304433	48/257 (19%)
adgrf6	XP_021324327.1	EGF_CA	216..249	CDD:214542
		EGF_CA	568..602	CDD:214542
		EGF_CA	920..954	CDD:214542
		EGF_CA	1272..1306	CDD:214542
		EGF_CA	1624..1658	CDD:214542
		EGF_CA	1976..2013	CDD:214542
		EGF_CA	2680..2717	CDD:214542
		EGF_CA	3384..3417	CDD:214542
		EGF_CA	3736..3769	CDD:214542
		EGF_CA	4088..4121	CDD:214542
		EGF_CA	4440..4477	CDD:214542
		EGF_CA	4792..4829	CDD:214542
		EGF_CA	5144..5181	CDD:214542
		EGF_CA	5496..5533	CDD:214542
		EGF_CA	5848..5885	CDD:214542
		EGF_CA	6904..6941	CDD:214542
		EGF_CA	7256..7293	CDD:214542
		EGF_CA	7608..7641	CDD:214542
		EGF_CA	7657..7695	CDD:311536
		EGF_CA	7706..7739	CDD:214542
		EGF_CA	7755..7789	CDD:214542
		EGF_CA	7804..7842	CDD:311536
		EGF_CA	7853..7886	CDD:214542
		EGF_CA	7902..7940	CDD:311536
		EGF_CA	7951..7984	CDD:214542
		EGF_CA	8000..8038	CDD:311536
		EGF_CA	8049..8082	CDD:214542
		EGF_CA	8098..8131	CDD:214542
		EGF_CA	8147..8185	CDD:311536
		EGF_CA	8196..8229	CDD:214542
		EGF_CA	8245..8278	CDD:214542
		EGF_CA	8294..8332	CDD:311536
		EGF_CA	8343..8376	CDD:214542
		EGF_CA	8392..8430	CDD:311536
		EGF_CA	8441..8474	CDD:214542
		EGF_CA	8490..8523	CDD:214542
		EGF_CA	8539..8577	CDD:311536
		EGF_CA	8588..8622	CDD:214542
		EGF_CA	8637..8675	CDD:311536
		EGF_CA	8686..8719	CDD:214542
		EGF_CA	8735..8769	CDD:214542
		EGF_CA	8784..>8816	CDD:214542
		EGF_CA	8879..8912	CDD:214542
		EGF_CA	8928..>8960	CDD:214542
		EGF_CA	9072..9110	CDD:311536
		EGF_CA	9121..9154	CDD:214542
		EGF_CA	9170..9208	CDD:311536
		EGF_CA	9219..9253	CDD:214542
		EGF_CA	9268..9306	CDD:311536
		EGF_CA	9317..9350	CDD:214542
		EGF_CA	9366..9404	CDD:311536
		EGF_CA	9415..9449	CDD:214542
		EGF_CA	9513..9550	CDD:311536
		EGF_CA	9562..9595	CDD:214542
		EGF_CA	9611..9649	CDD:311536
		EGF_CA	9660..9694	CDD:214542
		EGF_CA	9758..9796	CDD:311536
		EGF_CA	9856..9894	CDD:311536
		EGF_CA	9905..9939	CDD:214542
		EGF_CA	9954..9992	CDD:311536
		EGF_CA	10003..10037	CDD:214542
		EGF_CA	10052..10090	CDD:311536
		EGF_CA	10101..10134	CDD:214542
		EGF_CA	10150..10188	CDD:311536
EGF_CA	10248..10286	CDD:311536
EGF_CA	10346..10384	CDD:311536
EGF_CA	10395..10428	CDD:214542
EGF_CA	10444..10482	CDD:311536
EGF_CA	10493..10527	CDD:214542
EGF_CA	10541..>10573	CDD:214542
Ig	<10867..>10910	CDD:325142
GAIN	11087..>11205	CDD:318649
GPS	11292..11337	CDD:307782	10/48 (21%)
7tmB2_GPR116-like_Adhesion_VI	11345..11611	CDD:320598	58/306 (19%)
TM helix 1	11347..11372	CDD:320598	5/24 (21%)
TM helix 2	11387..11409	CDD:320598	3/21 (14%)
TM helix 3	11422..11449	CDD:320598	10/50 (20%)
TM helix 4	11463..11483	CDD:320598	5/20 (25%)
TM helix 5	11503..11532	CDD:320598	5/28 (18%)
TM helix 6	11549..11575	CDD:320598	7/26 (27%)
TM helix 7	11579..11604	CDD:320598	7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910