DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl3 and adgrg6

DIOPT Version :9

Sequence 1:NP_001286526.1 Gene:mthl3 / 36961 FlyBaseID:FBgn0028956 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001356058.1 Gene:adgrg6 / 561970 ZFINID:ZDB-GENE-041014-357 Length:1208 Species:Danio rerio


Alignment Length:333 Identity:76/333 - (22%)
Similarity:134/333 - (40%) Gaps:65/333 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 SKREYC----VQHLSFKDDSIRIAPHFCPLSSEHSRTWKTVAIV---ISLICIILTISVYLYVEK 238
            |.|..|    :.|.....|..|.|.   .:..:::|....:..:   ||.|....|:..|:..||
Zfish   785 SNRTVCLCNHLTHFGIL
MDVSRAAE---LIDEKNNRVLTFITYIGCGISAIFSAATLLTYIAFEK 846

  Fly   239 LRNLHGKCFICYLAS--LFLGYFFLVLNVWKYS---SGFCVTAGFLGYFSVIAAFFWLSVISLTL 298
            ||..:....:..|::  |||...|| |:.|..|   ...|||.....:|.::.:|.|:.:.|:.:
Zfish   847 LRRDYPSKILMNLSTSLLFLNMVFL-LDGWLASYEIKELCVTVAVFLHFFLLTSFTWMGLESIHM 910

  Fly   299 WNSF-SGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAITYIA--DQVVKNEKLRPRVGVGKN--C 358
            :.:. ...::::.|::     |.:.:..||:...:..|....  |...||...:.:.|.|.:  |
Zfish   911 YIALVKVFNTYIRRYI-----LKFCIVGWGVPAAIVGIVLAVSKDSYGKNYYGKGKDGQGTSEFC 970

  Fly   359 WI------YTGDMTVMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEAQNFTQQQKTTNRLNSDK 417
            ||      |   :|.:.||    .:|.:.|:.||::...:|.....:..|.|.::.....|.|  
Zfish   971 WILNPVVFY---VTCVAYF----SIIFLMNVAMFIVVMIQICGRNGKRSNRTLREDILRNLRS-- 1026

  Fly   418 QTYALFLRLFIIMGLSWSLEIISFLLSKNQAW---AKAFM-VADYFNWSQGTVIFLLFVLRPSTL 478
                 .:.|..::|::|.....        ||   :.||| :...||..||..||:...      
Zfish  1027 -----VVSLTFLLGMTWGFAFF--------AWGPVSLAFMYLFTIFNSLQGLFIFVFHC------ 1072

  Fly   479 KLLKERIK 486
             .|||.::
Zfish  1073 -ALKENVQ 1079

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl3NP_001286526.1 Methuselah_N 26..204 CDD:284145 7/26 (27%)
7tm_4 216..436 CDD:304433 54/238 (23%)
adgrg6NP_001356058.1 CUB 41..146 CDD:278839
LamG 153..336 CDD:354964
GPS 756..801 CDD:334696 4/15 (27%)
7tmB2_GPR126 816..1086 CDD:320662 69/299 (23%)
TM helix 1 818..843 CDD:320662 5/24 (21%)
TM helix 2 853..875 CDD:320662 7/22 (32%)
TM helix 3 886..913 CDD:320662 6/26 (23%)
TM helix 4 928..944 CDD:320662 2/15 (13%)
TM helix 5 975..998 CDD:320662 7/29 (24%)
TM helix 6 1021..1046 CDD:320662 6/39 (15%)
TM helix 7 1050..1075 CDD:320662 9/31 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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