Protein Alignment mthl3 and adgrv1

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_009300028.1
• Gene: adgrv1 / 415105
• ZFINID: ZDB-GENE-040624-6
• Length: 6208
• Species: Danio rerio
• Alignment Length: 356
• Identity: 67/356 - (18%)
• Similarity: 122/356 - (34%)
• Gaps: 97/356 - (27%)

  Fly   170 SLLRHWDKVE---LSKREYCVQHLSFKDDSIRIAPHFCPLSSEHSRTWKTVAIVISL-------- 223
            ||...|::..   ||..::|    ...||:    .::...:..|...:...|.:.||
Zfish  5758 SLCLLWNQAAESWLSDGQFC----RLVDDT----QNYVECACSHLSIYTAYAEIESLASFNEAFY 5814

  Fly   224 ----ICI----------ILTISVYLYVEK-LRNLHGKCF---ICYLASLFLGYFFLVLNVWKYSS 270
                |||          ::.....::..| |.::...|.   ||:|.|.|.|..|        |.
Zfish  5815 AAGFICISGFALAMVSHLMCARFLMFAAKLLTHMMVACLGTQICFLVSAFRGRMF--------SE 5871

  Fly   271 GFCVTAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAI 335
            ..|...|...::..::.|.|:.|.::..|.....|.....|     |:|.|.|.:||:..|:..:
Zfish  5872 DSCAALGLFFHYFHLSQFSWMLVQAINFWQILVMNDEHTER-----RYLLYFLLSWGLPALVIIV 5931

  Fly   336 TYIADQVVKNEKLRPRVGVGKNCW-------IYTGDMTVMIYFYGPML------LIIVFNITMFV 387
            ..:             |.:|...|       :..||:..:...|..:.      ||.:..:.:..
Zfish  5932 LVV-------------VLLGGFGWSIHSVYGLVQGDLCFIPNVYAALCTAALVPLICLVGVLVIF 5983

  Fly   388 LTAFRIMKVKKEAQNFTQQQKT-----TNRLNSDKQTYALFLRLFIIMGLSWSLEIISFLLSKNQ 447
            :.|:::          |||.|.     ..|.||.:....|:|...:.:...|:    ...::...
Zfish  5984 IHAYQV----------TQQWKAYDDIYRGRTNSSEVPMMLYLFALVTLVCVWA----GLHMAYRY 6034

  Fly   448 AWAKAFMVADYFNWSQGTVIFLLFVLRPSTL 478
            .|....:|  .||...|..:|.::.:..:.|
Zfish  6035 IWMLILLV--IFNIFLGLYVFSVYFVMHNQL 6063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	8/36 (22%)
		7tm_4	216..436	CDD:304433	51/263 (19%)
adgrv1	XP_009300028.1	Calx-beta	138..230	CDD:295344
		Calx-beta	256..355	CDD:295344
		Calx-beta	766..853	CDD:295344
		Calx-beta	880..971	CDD:295344
		Calx-beta	996..1082	CDD:295344
		Laminin_G_3	1343..1484	CDD:290121
		Calx-beta	1576..1654	CDD:295344
		Calx-beta	1712..1794	CDD:295344
		Calx-beta	1849..1939	CDD:295344
		Calx-beta	1975..2065	CDD:295344
		Calx-beta	2105..2193	CDD:295344
		Calx-beta	2220..2310	CDD:295344
		Calx-beta	2590..2656	CDD:295344
		Calx-beta	2951..3039	CDD:295344
		Calx-beta	<3574..3614	CDD:295344
		Calx-beta	3641..3729	CDD:295344
		Calx-beta	<3788..3864	CDD:295344
		Calx-beta	4021..4112	CDD:295344
		Calx-beta	4257..4345	CDD:295344
		Calx-beta	4390..4480	CDD:295344
		Calx-beta	5003..5085	CDD:295344
		7tm_4	<5871..>5926	CDD:304433	14/59 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900