Protein Alignment mthl3 and mthl5

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001287291.1
• Gene: mthl5 / 41438
• FlyBaseID: FBgn0037960
• Length: 497
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 94/476 - (19%)
• Similarity: 180/476 - (37%)
• Gaps: 84/476 - (17%)

  Fly    73 VASHVRGC----ACHLRP---CIRFCCPQYQKMQKSKCYGDMSEDELNKHDPFVNVTLSDGSVVR 130
            |.|||...    |....|   .:..||.:::.....:|      .::|:.|.|..:..|.|....
  Fly    41 VTSHVTSAGSSTALSSDPNLVLVNKCCEKFEIHVDHEC------QQVNETDYFQPMFTSYGGEQN 99

  Fly   131 RHFKEDLIVQSDLAKPGCPRMYFLNHELPGNEFTLFENGSLLRHWDKVELSKRE----------- 184
            |..|...::  .:...|..:|:.:.|....::..:..:...|||:...|....|
  Fly   100 RPVKFKFVI--GIPNCGSMQMWPIYHYAGSSDKLVLLDDGRLRHYTNAENEAEERHGIQSDYEED 162

  Fly   185 ----------------YCVQHL--SFKDDSIRIAPHFCPLSSEHSRTWKTVAIV----------- 220
                            ||:...  |..::::..| :.|....|..  |.....:
  Fly   163 IAGSLEPLYHDYDKGLYCIDKATSSTGEENVLFA-NICLARKEIK--WSDSNFLLRKILNPIFHG 224

  Fly   221 ISLICIILTISVYLYVEKL-RNLHGKCF----ICYLASLFLGYFFLVLNVWKYSSGFCVTAGFLG 280
            |||:.:::...:|..:..| |:|.|...    :|.:.|.......:...:..:.|  .:.|..:.
  Fly   225 ISLVILLVIAIIYFILPTLSRDLVGNIVTTIAMCLMVSQAADLVRIFTELTSHVS--FIVADIIL 287

  Fly   281 YFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAITYIADQVVKN 345
            .||::||||||:.....:|.:|...:.:| |.....::..|:.||||....:.|:...|...:..
  Fly   288 CFSLLAAFFWLNSFGFYIWKTFRSRNVFL-RVTDGRKYCYYSAYAWGCTATMAALAVFAHFFLDA 351

  Fly   346 EKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEAQNFTQQQKTT 410
            |..:....||:...|  |.:.:.| |:.|:...|:.||..:|.|       :|.....|...:..
  Fly   352 ESYKQEHMVGEQETI--GWLGICI-FFAPIACTILVNIFFYVTT-------RKLINRRTVYGRIA 406

  Fly   411 NRLNSDKQTYALFLRLFIIMGLSWSLEIISFLLSKNQAWAKAFMVADYFNWSQGTVIFLLFVLRP 475
            ::|   |..:.:|..:.::|.::|...|:|:|..:...:|...:     |..|..::..:.|||.
  Fly   407 HKL---KANFIMFSLMLLVMSIAWLFLIMSWLQMEGLLYAHIVV-----NALQTPLLLYICVLRQ 463

  Fly   476 STLKLLKERIKGGRDEAGASD 496
            ..:..|.::.....:...|:|
  Fly   464 RHVTFLLKKTCCYNEPPSAND 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	28/166 (17%)
		7tm_4	216..436	CDD:304433	51/235 (22%)
mthl5	NP_001287291.1	7tm_4	212..451	CDD:304433	56/259 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810