Protein Alignment mthl3 and ADGRD2

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001382354.1
• Gene: ADGRD2 / 347088
• HGNCID: 18651
• Length: 982
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 79/363 - (21%)
• Similarity: 133/363 - (36%)
• Gaps: 93/363 - (25%)

  Fly   189 HLSFKDDSIRIAPHFCPLSSEHSRTWKTVAIVISLICIILT-----------ISVYLY-VEK--- 238
            ||..:..|....||  |.|......|.|....::.:.:..|           |.:.:| |::
Human   628 HLQHRAQSPLFPPH--PPSPYTGGAWATTGCSVAALYLDSTACFCNHSTSFAILLQIYEVQRGPE 690

  Fly   239 ----LRNLH----GKCFICYLASLFLGYF-------------------------FLVLNVW-KYS 269
                ||.|.    |..| |.|.:.||.:.                         ||:.:.| |.:
Human   691 EESLLRTLSFVGCGVSF-CALTTTFLLFLVAGVPKSERTTVHKNLTFSLASAEGFLMTSEWAKAN 754

  Fly   270 SGFCVTAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLTA 334
            ...||......:|..:.||.|:.|..|.||......|     ..|......|:...||:.:.:.|
Human   755 EVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVS-----MHPGPGMRLYHATGWGVPVGIVA 814

  Fly   335 ITYIADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLIIVFN------ITMFVLTAFRI 393
            :|.   .::.::.:.|     .:||:......:.. |.||:|.::..|      :.|..:::.|.
Human   815 VTL---AMLPHDYVAP-----GHCWLNVHTNAIWA-FVGPVLFVLTANTCILARVVMITVSSARR 870

  Fly   394 MKVKKEAQNFTQQQKTTNRLNSDKQTYAL---FLRLFIIMGLSWSLEIISFLLSKNQAWAKAFMV 455
            .......|...|||..|       |.:|.   .|.|..::||:|   :...|:..:.|||.|
Human   871 RARMLSPQPCLQQQIWT-------QIWATVKPVLVLLPVLGLTW---LAGILVHLSPAWAYA--- 922

  Fly   456 ADYFNWSQGTVIFLLFV-----LRPSTLKLLKERIKGG 488
            |...|..||..|||::.     :|.:..::.::::..|
Human   923 AVGLNSIQGLYIFLVYAACNEEVRSALQRMAEKKVAEG 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	5/14 (36%)
		7tm_4	216..436	CDD:304433	57/277 (21%)
ADGRD2	NP_001382354.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810