Protein Alignment mthl3 and adgrg1

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001018317.1
• Gene: adgrg1 / 324948
• ZFINID: ZDB-GENE-030131-3671
• Length: 648
• Species: Danio rerio
• Alignment Length: 584
• Identity: 109/584 - (18%)
• Similarity: 196/584 - (33%)
• Gaps: 217/584 - (37%)

  Fly    43 GSYLYEGLLIPAHLTAEYDYKLLADDSKEKVASHVRGCACHLRP---------CIRF-------- 90
            |:|:::|    ||:           :.|||.....|     |:|         .:||
Zfish   160 GNYIFDG----AHI-----------NCKEKFCDEAR-----LKPRGANMIEEVVMRFNAKGRVDL 204

  Fly    91 CCPQYQKMQKSKCYGDMSEDELNKHD--------------PFVNVTLSDGSVVRRHFKEDLIVQS 141
            .|.|...::        .::|...|:              |.|.:..|..||.||.
Zfish   205 PCAQGTVIE--------MDEEFTGHNFTVPAPRFVDANTIPSVYIPSSLRSVSRRK--------- 252

  Fly   142 DLAKPGCPRMYFLNHELPGNEFTLFENG----SLLRHWDKVELSKREYCVQHLSFKDDSIRIAPH 202
              :|..|  .|:.|.       ||||.|    :||.  |.|.||.....:::|.   :.::|..|
Zfish   253 --SKVVC--TYYKNK-------TLFERGPSKSALLD--DIVGLSVENETIRNLI---EPVKIRFH 301

  Fly   203 ---FCPLSSEHSRTWKT------------------------------------------------ 216
               |.|.||....:|.|
Zfish   302 HRPFAPDSSGRCVSWDTKQDNEVNWKDDGCDTVKINEEQTECHCNHLTYFAILVQVEQKSTVRHL 366

  Fly   217 --------VAIVISLI-CIILTISVYLYVEKLRNLHGKCFICY---LASLFLGYFFLVL-----N 264
                    |...:||: |::|   .|...::.|....:..:.:   :.::||...|.:|     |
Zfish   367 KALTFITAVGCAVSLVSCLVL---FYWLCKRRRGKKNQISLVHRGLVVAIFLLCLFFILTGILAN 428

  Fly   265 VWKYSSGFCVTAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYAWGMA 329
            |  .:...|...|.|.::.:::...|:   ::.::::|.......|..||   ...:.|..:|..
Zfish   429 V--ANETVCQLTGSLLHYGLLSTLCWM---AMEVFHTFLLVRKVFNSPLP---IWIFYLMGFGFP 485

  Fly   330 LLLTAITYIADQVVKNEKLRPRVGVG---KNCWIYTGDMTVMIYF---YGPMLLIIVFNITMFVL 388
            .||.:|......:....|::|...|.   :.||:..||.:.:.::   .|.:.:::...:.|..|
Zfish   486 FLLVSILLSVGDIYGERKIKPSDDVNNPYRMCWMTEGDKSQLAHYIINIGLLAVVVSSGLVMLFL 550

  Fly   389 TAFRIMKVKKEAQNFTQQQKTTNRLNSD-KQTYALFLRLFIIMGLSWSLEIISFLLSKNQAWAKA 452
                   |.:|.:|           ..| |:.:..||.:       |.|..:     ....||..
Zfish   551 -------VVREIRN-----------RPDWKKIHVAFLSI-------WGLTCL-----YGTTWALG 585

  Fly   453 FMVADYFNWSQGTVIFLLFV---------LRPSTLKLLKERIKGGRD--EAGASDEHISLQNTK 505
            |:  |:..:|:.|:.....:         ||...|:.:|::.....|  .:|:|.:|:...|.|
Zfish   586 FL--DFGPFSEVTLFLFCIINSLQGFFLMLRYYALERMKKKDVSSSDGSSSGSSKQHMLQTNEK 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	42/198 (21%)
		7tm_4	216..436	CDD:304433	45/291 (15%)
adgrg1	NP_001018317.1	GPS	312..354	CDD:280071	2/41 (5%)
		7tm_4	369..611	CDD:304433	51/284 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900