Protein Alignment mthl3 and mthl15

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_723538.3
• Gene: mthl15 / 318914
• FlyBaseID: FBgn0051720
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 445
• Identity: 123/445 - (27%)
• Similarity: 196/445 - (44%)
• Gaps: 85/445 - (19%)

  Fly    77 VRGC----ACHLRPCIRFCCPQYQKMQKSKCYGDMSEDELNKHDPFVNVTLSDGSVVRRHFKEDL 137
            ||.|    .|...||||.||               :|.|:.....|......||:..:....::|
  Fly   247 VRACQEMKICQKIPCIRRCC---------------AEGEMYAKGNFSTYCKIDGTDFKFEGFQNL 296

  Fly   138 IVQSDLAKPG---------CPRMYFLNHELPGNEFTLF-ENGSLLRHWDKVELSKREYCVQH--- 189
            .:.::.:||.         ||:........|.:..|:. .||||:.|......:..:|||:.
  Fly   297 NINANFSKPSDFGIVHGLQCPKFRLDPDNFPDDSHTINPSNGSLIIHNTFKTYTNTQYCVERVRP 361

  Fly   190 -------LSFKD-----DSIRIAPHFCPLSSEHSRTWKTVAIVISLICIILTISVYLYVEKLRNL 242
                   |.|.:     |.||...:             .:.::||.....||:.||:.:.|||||
  Fly   362 NQKLYTFLCFDNKVVTGDRIRFKMY-------------PIGLLISCCFYALTLIVYISIAKLRNL 413

  Fly   243 HGKCFICYLASLFLGYFFLVLNVWKYSSG--FCVTAGFLGYFSVIAAFFWLSVISLTLWNSF--- 302
            .||..||.::|||..|..:.|...:.:|.  .|..:||..||.::|||.|:::.|..:|.:|
  Fly   414 PGKILICLVSSLFAAYLGIALGQLRPTSNDDICFLSGFFVYFCLMAAFSWMNITSFDIWKTFGST 478

  Fly   303 ---SGNSSWLNRFLPQNRFLSYNLYAWGMALLLTAITY-IADQVVKNEKLRPRVGVGKNCWIYTG 363
               |...|.|.|     :|:.|:.|.||:..|||.||. .....:..:.:||..|.|: || :|.
  Fly   479 KLKSCEKSDLRR-----QFIWYSCYGWGLPTLLTGITIAFTKSDILPDAVRPNFGHGR-CW-FTY 536

  Fly   364 D---MTVMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEAQNF----TQQQKTTNRLNSDKQTYA 421
            |   ...:::|.||:.::.:.|:.:||||.....|||.|....    :.:.....|...||..:.
  Fly   537 DSFGSASLLFFSGPVGILFIINLVLFVLTMKYCNKVKNEIYKMQSLNSDKPVLKRRFFQDKTRFV 601

  Fly   422 LFLRLFIIMGLSWSLEIISFLLSKNQAWAKAFM--VADYFNWSQGTVIFLLFVLR 474
            :..:|..:||::|.|||:|.|...::   |.|.  ::|.||...|..:|::||.:
  Fly   602 MNTKLCFVMGITWLLEIVSILFYDHK---KTFFWTISDSFNVLLGIFVFIIFVFK 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	35/155 (23%)
		7tm_4	216..436	CDD:304433	74/235 (31%)
mthl15	NP_723538.3	Mth_Ecto	<247..355	CDD:299804	27/122 (22%)
		7tm_4	385..646	CDD:304433	85/283 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.070