Protein Alignment mthl3 and mthl13

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_788325.2
• Gene: mthl13 / 246395
• FlyBaseID: FBgn0050018
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 132/498 - (26%)
• Similarity: 222/498 - (44%)
• Gaps: 85/498 - (17%)

  Fly     4 VIGSFTAFLLLLLQNSNAEIPGCDFFDTVDISKAPRFSNGSYLYEGLLIPAHLTAEYDYKLLADD 68
            ::|:|...:||..|..|.:                  ||              ..|.|..:.:||
  Fly     5 LLGTFLVLILLQFQAVNTD------------------SN--------------KTEEDSCVKSDD 37

  Fly    69 SKEKVASHVRGCACHLRPCIRFCCPQYQKMQKSKCYGDMSEDELNKHDPFVNVTLSDGSVVRRHF 133
            .......       .|..||..|||:...|....|   ..::.|.:....:|:.|.|.|....:|
  Fly    38 DNSNDED-------DLWHCIPICCPRKNMMANGGC---SFKEHLFRTKLDLNIRLDDNSTEALYF 92

  Fly   134 -KEDLIVQSDLAKPGCPRMYFLNHELPG---NEFTLFENGSLLRHWDKVELSKREYC-VQHLSFK 193
             .:.|::.|          ::...|:.|   :|:||::||::..|.|:...:|.||| ..|..:.
  Fly    93 NNQTLLITS----------FWDIDEMMGLRRDEYTLYKNGTIYIHSDQSIQTKEEYCFYPHQIYS 147

  Fly   194 D--DSIRIAPH-FCPLSSEHSRTWKTVAIVISLICIILTISVYLYVEKLRNLHGKCFICYLASLF 255
            |  ::|.|..| |..:.|..:....:.    |:||.|:...:||:|::|||..|||.:..:..||
  Fly   148 DFPETIWIISHKFSSIESPGAFELASG----SIICYIIIFGIYLFVKELRNDFGKCVMSCVFCLF 208

  Fly   256 LGYFFLVLNVWKYSSGFCVTAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLS 320
            |.|...:::..:....||...|::.:|...|...|.|:||..:|...:...|..||    ::|:.
  Fly   209 LDYLIWLMDELRLLDDFCSLTGYIMFFFDFANSVWFSIISYCIWKKITSVVSQENR----DQFVF 269

  Fly   321 YNLYAWGMALLLTAITYIADQVVKNEKLR-----PRVGVGKNCWIYTGDMTVMIYFYGPMLLIIV 380
            |:.:|:|::.:...|....:|..: |.||     |.||..: |.:.....:..:|::.|..::..
  Fly   270 YSTFAYGISAIPLGIIISINQFWE-EDLRKWNWLPLVGFSR-CSVDDCKRSSWVYYFVPYAIMCA 332

  Fly   381 FNITMFVLTAFRIMKVKKEAQNFTQQQK------TTNRLNSDKQTYALFLRLFIIMGLSWSLEII 439
            .||.|||||...|||.|:...|.|::..      |.|.||.  :.|.||||:..|||::|.| ||
  Fly   333 INIIMFVLTIKHIMKTKRNLHNLTKRPDRNETCVTVNFLNF--ELYLLFLRISGIMGVAWIL-II 394

  Fly   440 SFLLSKNQAWAKAF-MVADYFNWSQGTVIFLLFVLRPSTLKLL 481
            ..|:..|..:...| ::....::..|.::|:|.:.:.||.:||
  Fly   395 FLLIEVNSTFWDIFGIIIQQIHYGFGIILFVLLIFKRSTHQLL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	40/185 (22%)
		7tm_4	216..436	CDD:304433	71/230 (31%)
mthl13	NP_788325.2	Mth_Ecto	<49..158	CDD:299804	32/121 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970