Protein Alignment mthl3 and ADGRL3

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_016863418.1
• Gene: ADGRL3 / 23284
• HGNCID: 20974
• Length: 1586
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 63/279 - (22%)
• Similarity: 112/279 - (40%)
• Gaps: 60/279 - (21%)

  Fly   213 TWKTVAIVISLICIILTISVYLYVEKLRN----LH-GKCFICYLASLFLGYFFLVLNVWKYSSGF 272
            ||  |.|::||:|:::.|..:.:...|::    :| ..|...::|.|.   |.:.:|........
Human   949 TW--VGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELL---FLIGINRTDQPIAC 1008

  Fly   273 CVTAGFLGYFSVIAAFFWLSVISLTLW----NSFSGNSSWLNRFLPQNRFLSYNLYAWGMALLLT 333
            .|.|..|.:| .:|||.|:.:..:.|:    ..|....|         |...:.|..:||..|:.
Human  1009 AVFAALLHFF-FLAAFTWMFLEGVQLYIMLVEVFESEHS---------RRKYFYLVGYGMPALIV 1063

  Fly   334 AITYIADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIY-FYGPMLLIIVFNITMFVLTAFRIMK-- 395
            |::...|.        ...|..|.||:...  |..|: |.||..|||:.|:....:..:::..
Human  1064 AVSAAVDY--------RSYGTDKVCWLRLD--TYFIWSFIGPATLIIMLNVIFLGIALYKMFHHT 1118

  Fly   396 --VKKEAQNFTQQQKTTNRLNSDKQTYALFLRLFII--------MGLSWSLEIISFLLSKNQAWA 450
              :|.|:..........||         .|::.::|        :||:|:..:: ::.......|
Human  1119 AILKPESGCLDNINYEDNR---------PFIKSWVIGAIALLCLLGLTWAFGLM-YINESTVIMA 1173

  Fly   451 KAFMVADYFNWSQGTVIFL 469
            ..|.:   ||..||..||:
Human  1174 YLFTI---FNSLQGMFIFI 1189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145
		7tm_4	216..436	CDD:304433	53/241 (22%)
ADGRL3	XP_016863418.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810