Protein Alignment mthl3 and ADGRF2

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001355044.1
• Gene: ADGRF2 / 222611
• HGNCID: 18991
• Length: 708
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 77/323 - (23%)
• Similarity: 139/323 - (43%)
• Gaps: 60/323 - (18%)

  Fly   170 SLLRHWDK------VELSKREYCVQHLS--FKDDSIRIAPHFCPLSSEHSRTWKT-VAIVISLIC 225
            |:...||:      .|.|::..|....|  |...||.::||   :......|:.| |.:.||:..
Human   399 SVENRWDQQACKMIQENSQQAVCKCRPSKLFTSFSILMSPH---ILESLILTYITYVGLGISICS 460

  Fly   226 IILTISVYLYV------EKLRNLHGKCFICYLASLFLGYFFLVLNVWKYSSGF----------CV 274
            :||.:|:.:.|      .::..|...|.:...|:|      |:.:||...:.|          ||
Human   461 LILCLSIEVLVWSQVTKTEITYLRHVCIVNIAATL------LMADVWFIVASFLSGPITHHKGCV 519

  Fly   275 TAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYA--WGMALLLTAITY 337
            .|.|..:|..::.|||:...:|.:....    ..:...||:: .|..:|::  :|..|.:.|||.
Human   520 AATFFVHFFYLSVFFWMLAKALLILYGI----MIVFHTLPKS-VLVASLFSVGYGCPLAIAAITV 579

  Fly   338 IADQVVKNEKLRPRVGVGKNCWIYTGDMT-VMIYFYGPMLLIIVFNITMFVLTAFRIMKVKKEA- 400
            .|.:..|. .|||.:     ||: ..||| .::.|..|.|.|:|.|:....|.   |:|.::.|
Human   580 AATEPGKG-YLRPEI-----CWL-NWDMTKALLAFVIPALAIVVVNLITVTLV---IVKTQRAAI 634

  Fly   401 -QNFTQQQKTTNRLNSDKQTYALFLRLFIIMGLSWSLEIISFLLSKNQAWAKAFMVADYFNWS 462
             .:..|:.:...|::.:      ...|..::||:|...:.:.:..::.|:...|.:.:.|..|
Human   635 GNSMFQEVRAIVRISKN------IAILTPLLGLTWGFGVATVIDDRSLAFHIIFSLLNAFQVS 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	12/41 (29%)
		7tm_4	216..436	CDD:304433	60/241 (25%)
ADGRF2	NP_001355044.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810