DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl3 and LOC108181087

DIOPT Version :9

Sequence 1:	NP_001286526.1	Gene:	mthl3 / 36961	FlyBaseID:	FBgn0028956	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_021329169.1	Gene:	LOC108181087 / 108181087	-ID:	-	Length:	166	Species:	Danio rerio

Alignment Length:	163	Identity:	41/163 - (25%)
Similarity:	71/163 - (43%)	Gaps:	38/163 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   285 IAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLS-YNLYAWGMALLLTAIT-------YIADQ 341
            :|||.|:.|..|.||      |..::..|.::|.:. |.|..||:.:|:..||       |.||
Zfish     6 MAAFSWMLVEGLLLW------SKVVSVNLSEDRHMKYYYLIGWGLPVLIVTITLASASGKYTAD- 63

  Fly   342 VVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLIIVFNITMFV-LTAFRIMKVKKE----AQ 401
                          .:||:...: .|:..|.||::.||:.||.:.. :....|...|:.    |.
Zfish    64 --------------GHCWLSVQN-GVIWGFAGPVIFIIMVNIMILTRVVVITIATAKRRSLMMAL 113

  Fly   402 NFTQQQKTTNRLNSDKQTYALFLRLFIIMGLSW 434
            |.:.:::.:.::   :......|.|..|:||:|
Zfish   114 NNSPEEQISEQI---RAAVKAVLVLLPILGLTW 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145
mthl3	NP_001286526.1	7tm_4	216..436	CDD:304433	41/163 (25%)
LOC108181087	XP_021329169.1	7tm_GPCRs	<1..166	CDD:333717	41/163 (25%)
		TM helix 4	36..52	CDD:320095	5/15 (33%)
		TM helix 5	71..94	CDD:320095	8/23 (35%)
		TM helix 6	126..151	CDD:320095	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1153592at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010