Protein Alignment mthl3 and adgre5b.2

DIOPT Version :9

• Sequence 1: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_005160278.1
• Gene: adgre5b.2 / 101882660
• ZFINID: ZDB-GENE-121214-277
• Length: 693
• Species: Danio rerio
• Alignment Length: 450
• Identity: 95/450 - (21%)
• Similarity: 184/450 - (40%)
• Gaps: 83/450 - (18%)

  Fly   104 YGDMSEDELNKHDPFVNVTLSDGSVVRRHFKE--------DLIVQSDLAKPGCPRMYFLNHELPG 160
            |.||:......|.  .:.||.:.|..|.|..|        ..:|.:.::.|...::..|......
Zfish   277 YKDMNSSSDLSHK--TSRTLQEDSRKRLHVDEKKITYQLNSKVVTAVVSNPDTKKLSDLMMLTFT 339

  Fly   161 NEFTLFENGSLLR---HWDKVE-LSKREYCVQHLSFKDDSIRIAPHFCPLSS--------EHSRT 213
            :|....|:|.:..   :|::.| :.....||:..|   :|.....|:..|||        ....|
Zfish   340 HEEERAESGGVAYTCVYWNESEKVWSGRGCVKEWS---NSTHTVCHWSHLSSFAVLMALYPVQDT 401

  Fly   214 WKTVAI-----VISLICIILTISVYLY---VEKLRN-LHGKCFIC-YLASLFLGYFFLVLNVWKY 268
            :.:|.|     |:||:|:.|.|..:.:   ::..|| :|....:| ::|.|   .|...::....
Zfish   402 FASVLITRVGLVLSLLCLFLCILTFRFCRSIQGTRNSIHLHLSVCLFIADL---VFLCGISSTHN 463

  Fly   269 SSGFCVTAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSY-NLYA--WGMAL 330
            .....:.||.|.:| .::||.|:.:..:.|:...         .|..:..|.: .|||  :|:.|
Zfish   464 QVACAIVAGLLHFF-FLSAFCWMLLEGVQLYRMV---------VLVFHTTLKHLYLYAVGYGVPL 518

  Fly   331 LLTAITYIADQVVKNEKLRPR-VGVGKNCWIYTGDMTVMIYFYGPMLLIIVFNITMFVLTAFRIM 394
            ::.:|:.|.         .|: .|..|:||: :.:..:::.|:.|:.:|::.||.:|::|.:::
Zfish   519 VIVSISAIT---------FPKGYGTNKHCWL-SLEGYLILSFFAPVCIIVILNIIVFIITVWKL- 572

  Fly   395 KVKKEAQNFTQQQKTTNRLNSDKQTYALFLRLFIIMGLSWSLEIISFLLSKN--QAWAKAFMVAD 457
                 |..|:......::|:..:...|..:....::|.||....  ||..||  :.....|::
Zfish   573 -----ALKFSSLNPDLSKLHKIRSFLATAVAQLCVLGGSWVFGF--FLFQKNGTEVMLYLFII-- 628

  Fly   458 YFNWSQGTVIFLLFVLRPSTLKLLKERI--------KGGRDEAGASDEHISLQNTKIDPS 509
             .|..||.:||::..|....:::....:        |.|.........|.|.:..:.|.|
Zfish   629 -LNSLQGALIFIMHCLLSKQVRVEYHSLFVRMCPYKKKGDYSVSTEPSHSSQKRLQSDQS 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	23/111 (21%)
		7tm_4	216..436	CDD:304433	51/233 (22%)
adgre5b.2	XP_005160278.1	GPS	353..398	CDD:197639	10/47 (21%)
		7tm_4	406..637	CDD:304433	58/264 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910