DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mthl4 and adgre10

DIOPT Version :9

Sequence 1:NP_788394.1 Gene:mthl4 / 36960 FlyBaseID:FBgn0034219 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_021333746.1 Gene:adgre10 / 569655 ZFINID:ZDB-GENE-090313-152 Length:690 Species:Danio rerio


Alignment Length:276 Identity:62/276 - (22%)
Similarity:116/276 - (42%) Gaps:59/276 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   217 VISLICII----------LTISVYLYVEKLRNLHGKCFICYLASLFLGYFFLV-----LNVWKYS 266
            :::|:|:|          |:.::..:...:.|: .:..||  .||...:..|:     |::.:..
Zfish   415 LLNLVCVIVGLVFFSLALLSFALCQWSPGVNNV-ARINIC--ISLLSAHLLLLLTQQFLSLIRPQ 476

  Fly   267 SGFCVTAGFLGYFSVMAAFFWLSVIGIHLRI---KFSLASNCLHRLLPENPFRAYNLYAWGIPLI 328
            ...||....|.:|..::||.|:.:..:.|.|   ..|..|:....:| .|.|    |...|..:.
Zfish   477 QVLCVVIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQVSSRKKEVL-SNGF----LCVIGYVVA 536

  Fly   329 MTAITYTADQVVKNEKLRPRVGVG-KNCWIYTGDMTVMIYFYGPMLLLIAFNIIMFVLSAIYIYN 392
            :..::.:...|.:        |.| :.|||.. |......|.||:.:::..|:|:|:..:||:.:
Zfish   537 LIGVSVSIGMVPE--------GYGSEQCWIKM-DKGFFWSFLGPVCVILGLNVILFISISIYLNS 592

  Fly   393 IKKNVKGLVHKQQTNQQINDQQMFAIFLRL--FILMGLSWSFEILSFLLTKQQAWARALMVAD-- 453
            ..|.:...|.:.:       |....:|..|  |:::|..|   ||.|       :|...||.:  
Zfish   593 ALKKLNAEVSQLK-------QTKVMVFKTLGQFVILGCPW---ILGF-------FAHVNMVVEIV 640

  Fly   454 --YFNWSQGTIIFVLF 467
              ..|..|||.||:::
Zfish   641 FIIINSQQGTFIFLIY 656

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl4NP_788394.1 Methuselah_N 23..201 CDD:284145
7tm_4 213..>385 CDD:304433 40/186 (22%)
adgre10XP_021333746.1 GPS 360..406 CDD:197639
7tm_GPCRs 413..672 CDD:333717 62/276 (22%)
TM helix 1 413..437 CDD:320095 4/21 (19%)
TM helix 2 446..467 CDD:320095 6/23 (26%)
TM helix 3 481..503 CDD:320095 6/21 (29%)
TM helix 4 527..543 CDD:320095 3/19 (16%)
TM helix 5 561..584 CDD:320095 6/22 (27%)
TM helix 6 608..631 CDD:320095 8/32 (25%)
TM helix 7 635..660 CDD:320095 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.