DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl4 and Adgrg5

DIOPT Version :9

Sequence 1:NP_788394.1 Gene:mthl4 / 36960 FlyBaseID:FBgn0034219 Length:517 Species:Drosophila melanogaster
Sequence 2:NP_001139444.1 Gene:Adgrg5 / 382045 MGIID:2685955 Length:524 Species:Mus musculus


Alignment Length:292 Identity:58/292 - (19%)
Similarity:108/292 - (36%) Gaps:80/292 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 VAIVISLICIILTISVYLYVEKL--------RNLHGKCFICYLASLFLGYFFLV---LNVWKYSS 267
            |...||::..:|||.:|....|.        .||:|       :.|.|...||:   :.:.....
Mouse   250 VGCSISIVASLLTILLYAQSRKQSDSTTRIHMNLNG-------SVLLLNVTFLLSSQMTLPTMPR 307

  Fly   268 GFCVTAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLY----------- 321
            ..|.....:.:::::::..|:::.|.:|.:...               |.||.|           
Mouse   308 PVCKVLAAVLHYALLSSLTWMAIEGFNLYLFLG---------------RVYNAYIRRYLLKLCML 357

  Fly   322 AWGIPLIMTAITYTADQVVKNEKLRPRV---------GVG----KNCWIYTGDM-TVMIYFYGPM 372
            .||.|.::..:..    ::|:....|.|         |.|    ..|||.:..: ::::..||..
Mouse   358 GWGFPALLVLLLL----MIKSSVYGPCVTSLSKSQENGTGFQNVSMCWIRSPMVHSILVMGYGGF 418

  Fly   373 LLLIAFNIIMFVLSAIYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSF 437
            ..|  ||:::...:...:..::...|.|     :.....|.   |:.|.|.:|:|.:|:....||
Mouse   419 TSL--FNLVVLAWALWILCRLRAREKAL-----SPWAYRDT---AMVLGLTVLLGTTWTLAFFSF 473

  Fly   438 --LLTKQQAWARALMVADYFNWSQGTIIFVLF 467
              .|..|      |.:...||...|..:|:.|
Mouse   474 GVFLLPQ------LFLFTIFNSLYGFFLFLWF 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl4NP_788394.1 Methuselah_N 23..201 CDD:284145
7tm_4 213..>385 CDD:304433 39/206 (19%)
Adgrg5NP_001139444.1 GPS 184..228 CDD:366827
7tm_GPCRs 242..514 CDD:391938 58/292 (20%)
TM helix 1 244..268 CDD:341315 7/17 (41%)
TM helix 2 277..298 CDD:341315 7/27 (26%)
TM helix 3 311..333 CDD:341315 1/21 (5%)
TM helix 4 353..369 CDD:341315 3/15 (20%)
TM helix 5 405..428 CDD:341315 5/24 (21%)
TM helix 6 449..474 CDD:341315 8/27 (30%)
TM helix 7 478..503 CDD:341315 7/28 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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