Protein Alignment mthl4 and mthl3

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001286526.1
• Gene: mthl3 / 36961
• FlyBaseID: FBgn0028956
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 416/523 - (79%)
• Similarity: 454/523 - (86%)
• Gaps: 19/523 - (3%)

  Fly     1 MRILL---IAVLFLLMPKSNAEIPGCDFFDTVDISKAPRFSNGSYLYEGLLIPAHLTAEYDYKLL 62
            |||::   .|.|.||:..|||||||||||||||||||||||||||||||||||||||||||||||
  Fly     1 MRIVIGSFTAFLLLLLQNSNAEIPGCDFFDTVDISKAPRFSNGSYLYEGLLIPAHLTAEYDYKLL 65

  Fly    63 ADDSKEKVASHVRGCACHLRPCIRFCCPQYQKMQKSKCYGDMSEDELNKHDPFVNVTLSDGSVVR 127
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly    66 ADDSKEKVASHVRGCACHLRPCIRFCCPQYQKMQKSKCYGDMSEDELNKHDPFVNVTLSDGSVVR 130

  Fly   128 RHFKEDLIVQSDLAKPGCPRMYFLNHELPGNEFTLFENGSLLRHWDKVELSKREYCVQHLSFKDD 192
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   131 RHFKEDLIVQSDLAKPGCPRMYFLNHELPGNEFTLFENGSLLRHWDKVELSKREYCVQHLSFKDD 195

  Fly   193 SIRIAPHFCPLSSEHSRTWKTVAIVISLICIILTISVYLYVEKLRNLHGKCFICYLASLFLGYFF 257
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   196 SIRIAPHFCPLSSEHSRTWKTVAIVISLICIILTISVYLYVEKLRNLHGKCFICYLASLFLGYFF 260

  Fly   258 LVLNVWKYSSGFCVTAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLYA 322
            ||||||||||||||||||||||||:|||||||||.:.|...||..|:.|:|.||:|.|.:|||||
  Fly   261 LVLNVWKYSSGFCVTAGFLGYFSVIAAFFWLSVISLTLWNSFSGNSSWLNRFLPQNRFLSYNLYA 325

  Fly   323 WGIPLIMTAITYTADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLLIAFNIIMFVLSA 387
            ||:.|::|||||.|||||||||||||||||||||||||||||||||||||||:|.|||.||||:|
  Fly   326 WGMALLLTAITYIADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLIIVFNITMFVLTA 390

  Fly   388 IYIYNIKKNVKGLVHKQQTNQQIN-DQQMFAIFLRLFILMGLSWSFEILSFLLTKQQAWARALMV 451
            ..|..:||..:....:|:|..::| |:|.:|:||||||:||||||.||:||||:|.||||:|.||
  Fly   391 FRIMKVKKEAQNFTQQQKTTNRLNSDKQTYALFLRLFIIMGLSWSLEIISFLLSKNQAWAKAFMV 455

  Fly   452 ADYFNWSQGTIIFVLFILKPSILKLI---IAGGRQNLPGSHHNSRSKAARYNSTHTACEGSIADP 513
            ||||||||||:||:||:|:||.|||:   |.|||..            |..:..|.:.:.:..||
  Fly   456 ADYFNWSQGTVIFLLFVLRPSTLKLLKERIKGGRDE------------AGASDEHISLQNTKIDP 508

  Fly   514 NAY 516
            :.:
  Fly   509 SVF 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	177/177 (100%)
		7tm_4	213..>385	CDD:304433	146/171 (85%)
mthl3	NP_001286526.1	Methuselah_N	26..204	CDD:284145	177/177 (100%)
		7tm_4	216..436	CDD:304433	169/219 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449686
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25921
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.910