Protein Alignment mthl4 and ADGRD2

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001382354.1
• Gene: ADGRD2 / 347088
• HGNCID: 18651
• Length: 982
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 79/339 - (23%)
• Similarity: 129/339 - (38%)
• Gaps: 85/339 - (25%)

  Fly   186 HLSFKDDSIRIAPHFCPLSSEHSRTWKTVAIVISLICIILT-----------ISVYLY-VEK--- 235
            ||..:..|....||  |.|......|.|....::.:.:..|           |.:.:| |::
Human   628 HLQHRAQSPLFPPH--PPSPYTGGAWATTGCSVAALYLDSTACFCNHSTSFAILLQIYEVQRGPE 690

  Fly   236 ----LRNLH----GKCFICYLASLFLGYF-------------------------FLVLNVW-KYS 266
                ||.|.    |..| |.|.:.||.:.                         ||:.:.| |.:
Human   691 EESLLRTLSFVGCGVSF-CALTTTFLLFLVAGVPKSERTTVHKNLTFSLASAEGFLMTSEWAKAN 754

  Fly   267 SGFCVTAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLYAWGIPLIMTA 331
            ...||......:|..:.||.|:.|.|:.|..|....|  :|   |....|.|:...||:|:.:.|
Human   755 EVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVS--MH---PGPGMRLYHATGWGVPVGIVA 814

  Fly   332 ITYTADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLLIAFN------IIMFVLSAIYI 390
            :|..   ::.::.:.|     .:||:......:.. |.||:|.::..|      ::|..:|
Human   815 VTLA---MLPHDYVAP-----GHCWLNVHTNAIWA-FVGPVLFVLTANTCILARVVMITVS---- 866

  Fly   391 YNIKKNVKGLVHKQQTNQQINDQQMFAI--FLRLFILMGLSWSFEILSFLLTKQQAWARALMVAD 453
             :.::..:.|..:....|||..|....:  .|.|..::||:|...||..|   ..|||.|   |.
Human   867 -SARRRARMLSPQPCLQQQIWTQIWATVKPVLVLLPVLGLTWLAGILVHL---SPAWAYA---AV 924

  Fly   454 YFNWSQGTIIFVLF 467
            ..|..||..||:::
Human   925 GLNSIQGLYIFLVY 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	5/14 (36%)
		7tm_4	213..>385	CDD:304433	47/226 (21%)
ADGRD2	NP_001382354.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810