Protein Alignment mthl4 and adgrg1

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001018317.1
• Gene: adgrg1 / 324948
• ZFINID: ZDB-GENE-030131-3671
• Length: 648
• Species: Danio rerio
• Alignment Length: 510
• Identity: 93/510 - (18%)
• Similarity: 171/510 - (33%)
• Gaps: 192/510 - (37%)

  Fly    40 GSYLYEGLLIPAHLTAEYDYKLLADDSKEKVASHVRGCACHLRP---------CIRF-------- 87
            |:|:::|    ||:           :.|||.....|     |:|         .:||
Zfish   160 GNYIFDG----AHI-----------NCKEKFCDEAR-----LKPRGANMIEEVVMRFNAKGRVDL 204

  Fly    88 CCPQYQKMQKSKCYGDMSEDELNKHD--------------PFVNVTLSDGSVVRRHFKEDLIVQS 138
            .|.|...::        .::|...|:              |.|.:..|..||.||.
Zfish   205 PCAQGTVIE--------MDEEFTGHNFTVPAPRFVDANTIPSVYIPSSLRSVSRRK--------- 252

  Fly   139 DLAKPGCPRMYFLNHELPGNEFTLFENG----SLLRHWDKVELSKREYCVQHLSFKDDSIRIAPH 199
              :|..|  .|:.|.       ||||.|    :||.  |.|.||.....:::|.   :.::|..|
Zfish   253 --SKVVC--TYYKNK-------TLFERGPSKSALLD--DIVGLSVENETIRNLI---EPVKIRFH 301

  Fly   200 ---FCPLSSEHSRTWKT------------------------------------------------ 213
               |.|.||....:|.|
Zfish   302 HRPFAPDSSGRCVSWDTKQDNEVNWKDDGCDTVKINEEQTECHCNHLTYFAILVQVEQKSTVRHL 366

  Fly   214 --------VAIVISLI-CIILTISVYLYVEKLRNLHGKCFICY---LASLFLGYFFLVL-----N 261
                    |...:||: |::|   .|...::.|....:..:.:   :.::||...|.:|     |
Zfish   367 KALTFITAVGCAVSLVSCLVL---FYWLCKRRRGKKNQISLVHRGLVVAIFLLCLFFILTGILAN 428

  Fly   262 VWKYSSGFCVTAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLYAWGIP 326
            |  .:...|...|.|.::.:::...|:::...|   .|.|.....:..|   |...:.|..:|.|
Zfish   429 V--ANETVCQLTGSLLHYGLLSTLCWMAMEVFH---TFLLVRKVFNSPL---PIWIFYLMGFGFP 485

  Fly   327 LIMTAITYTADQVVKNEKLRPRVGVG---KNCWIYTGDMTVMIYF---YGPMLLLIAFNIIMFVL 385
            .::.:|..:...:....|::|...|.   :.||:..||.:.:.::   .|.:.::::..::|..|
Zfish   486 FLLVSILLSVGDIYGERKIKPSDDVNNPYRMCWMTEGDKSQLAHYIINIGLLAVVVSSGLVMLFL 550

  Fly   386 SAIYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLF---ILMGLSWSFEILSF 437
            ....|.|                :.:.:::...||.::   .|.|.:|:...|.|
Zfish   551 VVREIRN----------------RPDWKKIHVAFLSIWGLTCLYGTTWALGFLDF 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	42/198 (21%)
		7tm_4	213..>385	CDD:304433	36/242 (15%)
adgrg1	NP_001018317.1	GPS	312..354	CDD:280071	2/41 (5%)
		7tm_4	369..611	CDD:304433	45/248 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900